Chapter 23 Mechanisms of ER Stress in Retinal Disease Sylvia B. Smith Basic science and clinical investigations aimed at understanding mechanisms of retinal disease frequently focus on retinal tissue, specific…
Chapter 26 Basic Mechanisms of Pathological Retinal and Choroidal Angiogenesis Demetrios G. Vavvas, Joan W. Miller Introduction The vasculature of the eye is completely formed shortly after birth and is…
Chapter 143 Overview of Management of Posterior Uveal Melanoma Jerry A. Shields, Carol L. Shields Introduction Even though there continue to be numerous publications on management of uveal melanoma, the…
Chapter 119 Surgical Management of Choroidal Neovascularization and Subretinal Hemorrhage Mathew W. Aschbrenner, Matthew A. Thomas Choroidal neovascular membranes Introduction The growth of choroidal neovascular membranes (CNV) beneath the macula…
Chapter 33 Epigenetic Mechanisms of Retinal Disease Shikun He, Glenn Yiu, Peng Zhou, Dong Feng Chen Brief history The term “epigenetics” was coined by C. H. Waddington in the 1940s,…
Chapter 60 Coagulopathies Sandra Liakopoulos, Florian M.A. Heussen, SriniVas R. Sadda A variety of hereditary as well as acquired diseases belong to the group of coagulopathies – diseases that affect…
Chapter 50 Telescreening for Diabetic Retinopathy Rajiv Raman, Aditi Gupta, Tarun Sharma Introduction The criteria for human diseases amenable to screening approaches were defined by the World Health Organization in…
Chapter 64 Pathogenetic Mechanisms in Age-Related Macular Degeneration Alan C. Bird Introduction Age-related macular degeneration (AMD) can be divided into early and late stages. In early disease visual acuity is…
Chapter 63 Epidemiology and Risk Factors for Age-Related Macular Degeneration Johanna M. Seddon, Lucia Sobrin Age-related macular degeneration (AMD) is the leading cause of irreversible blindness.1 The disease adversely affects…
Chapter 30 Pathogenesis of Serous Detachment of the Retina and Pigment Epithelium Gisèle Soubrane, Gabriel Coscas Retinal detachment is defined as the accumulation of fluid between the neurosensory retina (NSR)…
