Fundus Autofluorescence in Age-Related Maculopathy Almut Bindewald-Wittich Robert P. Finger Frank G. Holz Age-related macular degeneration (AMD) has become the most common cause of severe visual loss in industrialized countries…
The Normal Distribution of Fundus Autofluorescence Theodore R. Smith This chapter concentrates on the image of the normal fundus itself and its analysis. In particular, it first discusses images obtained…
Quantifying Fundus Autofluorescence Dietrich Schweitzer INTRODUCTION The investigation of endogenous fluorophores has the potential to aid in evaluating the metabolic status of tissues and thus detecting the early stages of…
Interpreting Fundus Autofluorescence Alan C. Bird Interpretation of autofluorescence (AF) images with illumination at 488 nm (standard AF image) is based on the principle that the majority of the signal…
Near-Infrared Fundus Autofluorescence Ulrich Kellner Simone Kellner Fundus autofluorescence (FAF) derived from lipofuscin and its major fluorophor, A2E, has developed into an important noninvasive imaging technique in the last decade….
Imaging Techniques of Fundus Autofluorescence Steffen Schmitz-Valckenberg Fred W. Fitzke The imaging of fundus autofluorescence (AF) phenomena in vivo, as discussed in Chapter 1, was first demonstrated in the early…
Lipofuscin and Autofluorescence in Experimental Animal Models Heping Xu Fundus autofluorescence (AF) imaging is increasingly being used in ophthalmic practice to aid in the diagnosis and monitoring of patients with…
Lipofuscin: The Origin of the Autofluorescence Signal François Delori The retinal pigment epithelium (RPE) digests the tips of the outer segment of the photoreceptors, which are phagocytosed on a daily…
Lipofuscin of the Retinal Pigment Epithelium Michael E. Boulton Lipofuscin accumulation is strongly associated with retinal aging and the progression of age-related macular degeneration (AMD) (1). Such lipofuscin accumulation is…
Lipofuscin: The “Wear and Tear” Pigment Sabrina S. Seehafer David A. Pearce Many substances fluoresce spontaneously (autofluoresce, i.e., emit light of a particular wavelength) when illuminated by light of a…
