Fig. 3.1 (a) Histology of the human cornea stained with hematoxylin and eosin (H&E). (b) Corneoscleral border. (c) Limbal junction. Reprinted with permission from Takacs et al. [3] At the…
Fig. 7.1 Macular degeneration is caused by degeneration of the retina resulting in vision loss in the macula at the center of the visual field. As this simulated photographic representation…
Fig. 5.1 Summary graphic describing the stages of progenitor cell (blue) to retinal ganglion cell (green) transition, and the transcription factors and extrinsic, environmental signals known to be associated with…
Fig. 6.1 Diabetes is a vascular disease that can obliterate the capillary bed in the retina. Diabetic retinopathy begins with hemorrhages in the blood vessels around the retina (pictured above…
Fig. 11.1 Normal electroretinogram (ERG) Tracings. The a-wave and b-wave are noted where applicable Safety Concerns The normal human eye is generally considered an immune-privileged organ, but one of the…
2. Schaffler A, Buchler C (2007) Concise review: adipose tissue-derived stromal cells–basic and clinical implications for novel cell-based therapies. Stem Cells 25(4):818–827PubMedCrossRef 3. Pittenger MF, Mackay AM, Beck SC et…
Fig. 10.1 Zinc Finger Nucleases introduce site-specific DNA double strand break and the damaged gene is replaced by homologous recombination containing desired gene and a selective marker To date, gene…
Fig. 9.1 (a) Melanomasphere forming efficiency (MSFE) in non-adherent culture. Melanoma cells isolated from 16 primary tumours were grown in non-adherent culture in a complex medium at a density of…
Fig. 4.1 Diagrammatic summary of a three-step procedure to differentiate human ES cells into lens progenitor-like cells and lentoid bodies. (a) Diagram of three steps: noggin treatment (days 0–6), BMP4/BMP7/FGF2…
(1) Department of Pathology, Duke University Medical Center, Durham, NC, USA Abstract The uveal tract comprises the iris, the ciliary body, and the choroid, each of which has distinct…
