Thinner Choroid and Greater Drusen Extent in Retinal Angiomatous Proliferation Than in Typical Exudative Age-Related Macular Degeneration

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Thinner Choroid and Greater Drusen Extent in Retinal Angiomatous Proliferation Than in Typical Exudative Age-Related Macular Degeneration

Purpose To compare choroidal thickness and extent and density of drusen between eyes with typical exudative age-related macular degeneration (AMD) and eyes with retinal angiomatous proliferation (RAP). Design Observational case…

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Effects of Light Exposure, pH, Osmolarity, and Solvent on the Retinal Pigment Epithelial Toxicity of Vital Dyes

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Effects of Light Exposure, pH, Osmolarity, and Solvent on the Retinal Pigment Epithelial Toxicity of Vital Dyes

Purpose To investigate the in vitro effect of pH, osmolarity, solvent, and light interaction on currently used and novel dyes to minimize dye-related retinal toxicity. Design Laboratory investigation. Methods Retinal pigment…

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Predictive Value of Spectral-Domain Optical Coherence Tomography Features in Assessment of Visual Prognosis in Eyes With Neovascular Age-Related Macular Degeneration Treated With Ranibizumab

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Predictive Value of Spectral-Domain Optical Coherence Tomography Features in Assessment of Visual Prognosis in Eyes With Neovascular Age-Related Macular Degeneration Treated With Ranibizumab

Purpose To determine whether pretreatment (baseline) optical coherence tomography (OCT) features can be used as predictors of visual acuity outcome at 12 months in eyes with neovascular age-related macular degeneration treated…

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Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Versus Photodynamic Therapy for Idiopathic Choroidal Neovascularization

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Versus Photodynamic Therapy for Idiopathic Choroidal Neovascularization

Purpose To compare visual outcomes after intravitreal anti–vascular endothelial growth factor (VEGF) injection or photodynamic therapy (PDT) for idiopathic choroidal neovascularization (CNV). Design Retrospective study. Methods Among 29 eyes (28…

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Treatment of Diabetic Macular Edema With a Designed Ankyrin Repeat Protein That Binds Vascular Endothelial Growth Factor: A Phase I/II Study

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Treatment of Diabetic Macular Edema With a Designed Ankyrin Repeat Protein That Binds Vascular Endothelial Growth Factor: A Phase I/II Study

Purpose To evaluate the safety and bioactivity of MP0112, a designed ankyrin repeat protein (DARPin) that specifically binds vascular endothelial growth factor (VEGF) in patients with diabetic macular edema (DME)….

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Diffusion of Technologies for the Care of Older Adults With Exudative Age-Related Macular Degeneration

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Diffusion of Technologies for the Care of Older Adults With Exudative Age-Related Macular Degeneration

Purpose To determine patterns of diffusion of diagnostic tests and therapeutic interventions in the United States through 2010 for patients with newly diagnosed exudative macular degeneration (AMD). Design Retrospective longitudinal…

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Ocular Biometry in the Subtypes of Angle Closure: An Anterior Segment Optical Coherence Tomography Study

Jan 9, 2017 by in OPHTHALMOLOGY Comments Off on Ocular Biometry in the Subtypes of Angle Closure: An Anterior Segment Optical Coherence Tomography Study

Purpose To evaluate ocular biometric parameters in different subtypes of angle-closure disease in the Iranian population and compare them with normal eyes. Design Prospective, cross-sectional. Methods In this clinic-based study,…

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