Acquired Macular Disease Introduction The anatomic macula is defined as the area of the posterior retina containing at least two layers of nuclei within the ganglion cell layer. Clinically, this…

Acute Retinal Necrosis and Progressive Outer Retinal Necrosis Syndromes Caroline R. Baumal Jay S. Duker David Fischer The herpesvirus family includes herpes simplex virus (HSV), varicella-zoster virus (VZV), cytomegalovirus (CMV),…

Sickle Cell Disease Seema Garg Lee M. Jampol Maurice Rabb Donald A. Gagliano This chapter is dedicated to Maurice Rabb, M.D. (1932–2005), previous author of this chapter. Dr. Rabb devoted…

Rhegmatogenous Retinal Detachment Brian P. Connolly Carl D. Regillo Background Rhegmatogenous retinal detachments (RRDs) occur when fluid from the vitreous cavity passes through a retinal break into the potential space…

Cytomegalovirus Retinitis Tamara R. Vrabec MD1 Caroline R. Baumal MD2 2 Tufts University, Boston, MA, cbaumal@tufts-nemc.org 1 Geisinger Medical Center, 100 North Academy Avenue, Danville, PA 17822-2120, tvrunning@aol.com, 570 271…

Pathologic Correlates in Ophthalmoscopy Julie M. Rosenthal Alexander R. Gaudio Vitaliano B. Bernardino Jr. Edward A. Jaeger Learning the pathologic correlates in ophthalmoscopy is an integral part of ophthalmic education….

Retinitis Pigmentosa and Allied Retinal Diseases Eliot L. Berson Introduction Retinitis pigmentosa and allied retinal diseases are a significant cause of visual loss around the world. The problem is magnified…

Gyrate Atrophy Steve A. Arshinoff Kevin Leung Yi Ning J. Strube HISTORY Gyrate atrophy (GA) (MIM 258870) of the choroid and retina is a rare autosomal recessive disorder characterized by…

Choroideremia Radha P. Kohly Rajeev H. Muni Alan R. Berger Choroideremia (CHM, OMIM #303100*) is a rare X-linked, hereditary degenerative disease of the choroid, retinal pigment epithelium (RPE), and retina….

Optical Coherence Tomography in the Management of Age-Related Macular Degeneration David Rhee Darrell Baskin INTRODUCTION Since 1991, optical coherence tomography (OCT) has evolved from an experimental imaging system to an…