Lipofuscin: The Origin of the Autofluorescence Signal François Delori The retinal pigment epithelium (RPE) digests the tips of the outer segment of the photoreceptors, which are phagocytosed on a daily…
Lipofuscin of the Retinal Pigment Epithelium Michael E. Boulton Lipofuscin accumulation is strongly associated with retinal aging and the progression of age-related macular degeneration (AMD) (1). Such lipofuscin accumulation is…
Lipofuscin: The “Wear and Tear” Pigment Sabrina S. Seehafer David A. Pearce Many substances fluoresce spontaneously (autofluoresce, i.e., emit light of a particular wavelength) when illuminated by light of a…
Tumors and Related Lesions of the Pigment Epithelium Solitary Congenital Hypertrophy of the Retinal Pigment Epithelium General Considerations Tumors and related lesions of the retinal pigment epithelium (RPE) include congenital…
Surgical Management of Intraocular Tumors Surgical Management of Intraocular Tumors Surgical management of intraocular tumors has been mentioned in several parts of this book, but specific steps have not been…
Vascular Tumors of the Retina and Optic Disc Retinal Hemangioblastoma (Capillary Hemangioma) General Considerations Retinal vascular tumors include hemangioblastoma (capillary hemangioma), cavernous hemangioma, racemose hemangioma, and acquired vasoproliferative tumor. Each…
Intraocular Lymphoid Tumors and Leukemias Intraocular Lymphoid Tumors Introduction to Intraocular Lymphoid Lesions Tumors derived from lymphoid cells can sometimes develop in the eye and affect the uveal tract, retina,…
Metastatic Tumors to the Uvea, Retina, and Optic Disc Metastatic Tumors to the Intraocular Structures General Considerations Metastatic cancer probably represents the most common form of intraocular malignancy. There are…
Posterior Uveal Melanoma: Management Posterior Uveal Melanoma: Management In recent years, there have been advances in the management of posterior uveal melanoma, and several options are now available (1, 2,…
Glial Tumors of the Retina and Optic Disc Pseudoneoplastic Gliosis of the Retina General Considerations Lesions that originate from retina glial cells include reactive gliosis, nodular pseudoneoplastic gliosis, astrocytic hamartoma,…
