Intravitreal Bevacizumab for Macular Complications From Retinal Arterial Macroaneurysms
Pichi and associates are to be congratulated for their study on the intravitreal use of bevacizumab for the therapy of retinal macroaneurysms. In their multicenter trial on 38 eyes, Pichi…
Macular Pseudoholes With Lamellar Cleavage of Their Edge Remain Pseudoholes
Purpose To reappraise macular pseudohole characteristics using spectral-domain optical coherence tomography (OCT) and characteristics and postoperative outcomes of macular pseudoholes. Design Retrospective, observational case series. Methods In this institutional study,…
Thinner Choroid and Greater Drusen Extent in Retinal Angiomatous Proliferation Than in Typical Exudative Age-Related Macular Degeneration
Purpose To compare choroidal thickness and extent and density of drusen between eyes with typical exudative age-related macular degeneration (AMD) and eyes with retinal angiomatous proliferation (RAP). Design Observational case…
Combined Depth Imaging Technique on Spectral-Domain Optical Coherence Tomography
Purpose To describe a technique to obtain combined images of vitreoretinal and choroidal structures using spectral-domain (SD) optical coherence tomography (OCT) and to evaluate applicability in normal eyes and limitations…
Effects of Light Exposure, pH, Osmolarity, and Solvent on the Retinal Pigment Epithelial Toxicity of Vital Dyes
Purpose To investigate the in vitro effect of pH, osmolarity, solvent, and light interaction on currently used and novel dyes to minimize dye-related retinal toxicity. Design Laboratory investigation. Methods Retinal pigment…
Predictive Value of Spectral-Domain Optical Coherence Tomography Features in Assessment of Visual Prognosis in Eyes With Neovascular Age-Related Macular Degeneration Treated With Ranibizumab
Purpose To determine whether pretreatment (baseline) optical coherence tomography (OCT) features can be used as predictors of visual acuity outcome at 12 months in eyes with neovascular age-related macular degeneration treated…
Intravitreal Anti–Vascular Endothelial Growth Factor Therapy Versus Photodynamic Therapy for Idiopathic Choroidal Neovascularization
Purpose To compare visual outcomes after intravitreal anti–vascular endothelial growth factor (VEGF) injection or photodynamic therapy (PDT) for idiopathic choroidal neovascularization (CNV). Design Retrospective study. Methods Among 29 eyes (28…
Treatment of Diabetic Macular Edema With a Designed Ankyrin Repeat Protein That Binds Vascular Endothelial Growth Factor: A Phase I/II Study
Purpose To evaluate the safety and bioactivity of MP0112, a designed ankyrin repeat protein (DARPin) that specifically binds vascular endothelial growth factor (VEGF) in patients with diabetic macular edema (DME)….
Diffusion of Technologies for the Care of Older Adults With Exudative Age-Related Macular Degeneration
Purpose To determine patterns of diffusion of diagnostic tests and therapeutic interventions in the United States through 2010 for patients with newly diagnosed exudative macular degeneration (AMD). Design Retrospective longitudinal…
