Children’s Oncology Group (COG) Trials for Retinoblastoma
Fig. 21.1 Group B retinoblastoma superonasal to the optic nerve at staging examination under anesthesia and prior to treatment (a). After the first cycle of CEV systemic chemotherapy (2 days…
Retinoblastoma: Enucleation
Fig. 15.1 Key steps in the successful enucleation of a group E eye. Immediately after the peritomy, Tenon’s capsule is being spread widely and deeply between the rectus muscles with…
Trilateral Retinoblastoma
Fig. 20.1 Brain MRI of a 3-year-old girl with trilateral retinoblastoma. Axial (a), coronal (b), and sagittal (c) sequences show a pineal tumor with secondary hydrocephalus. Resection and subsequent histopathologic…
Conjunctival and Corneal Tumors: Ocular Surface Squamous Neoplasia
Fig. 16.1 A 52-year-old African woman was diagnosed with HIV, with a CD4 count of 56 × 106/mm3 and viral load >100,000 copies/mL. At presentation, a fleshy conjunctival growth extending onto the…
Benign Squamous and Melanocytic Tumors
Types Subtypes Non-melanocytic Benign Squamous cell papilloma Seborrheic keratosis Inverted follicular keratosis Molluscum contagiosum Reactive hyperplasia (pseudoepitheliomatous hyperplasia) Potentially premalignant Actinic (solar) keratosis Intraepithelial neoplasia Sebaceous nevus (of Jadassohn) Malignant…
Surgical Techniques
Fig. 10.1 Mohs’ micrographic surgery. Frozen sections are obtained from the undersurface and skin edges of the excised lesion. Locations of residual tumor are marked on a map for subsequent…
Caruncular Tumors
Pathologic diagnosis n % Melanocytic tumor Nevus 92 47 Dysplastic nevus 2 1 Primary acquired melanosis 1 0.5 Malignant melanoma 1 0.5 Benign epithelial tumor Papilloma 29 15 Sebaceous gland…
Stromal Tumors
Category Subtypes Vascular tumors Pyogenic granuloma Racemose malformation Capillary hemangioma Hemangiopericytoma Cavernous hemangioma Kaposi’s sarcoma Acquired sessile hemangioma Lymphangiectasia Varix Lymphangioma Malignant hemangioendothelioma Fibrous tumors Fibroma Nodular fasciitis Benign fibrous…
Conjunctival and Corneal Tumors: Melanoma
Fig. 18.1 Melanoma of the peri-limbal bulbar conjunctiva with “feeder vessels” entering the tumor Fig. 18.2 Conjunctival PAM with atypia, which has progressed to corneo-limbal melanoma Fig. 18.3 Melanoma of…
Conjunctival and Corneal Tumors: Benign Epidermal and Melanocytic Tumors
Fig. 15.1 Solitary sessile squamous papilloma of the bulbar conjunctiva. Clinical appearance (a). Histopathology shows papillomatous fronds of acanthotic nonkeratinized squamous epithelium with central fibrovascular cores (b; hematoxylin and eosin,…
