Fig. 1.1 Autofluorescence imaging of the retinal pigment epithelium (RPE), demonstrating the topographic distribution of fluorescence in the posterior segment of the human eye. Many fluorophores are contained within RPE,…
Fig. 8.1 Shows an EM autoradiogram revealing tritiated thymidine grains (TT) present in the nuclei of transplanted human RPE in owl monkey retina several days after surgery We then sought…
Fig. 5.1 Summary graphic describing the stages of progenitor cell (blue) to retinal ganglion cell (green) transition, and the transcription factors and extrinsic, environmental signals known to be associated with…
Fig. 7.1 Macular degeneration is caused by degeneration of the retina resulting in vision loss in the macula at the center of the visual field. As this simulated photographic representation…
Fig. 3.1 (a) Histology of the human cornea stained with hematoxylin and eosin (H&E). (b) Corneoscleral border. (c) Limbal junction. Reprinted with permission from Takacs et al. [3] At the…
Fig. 6.1 Diabetes is a vascular disease that can obliterate the capillary bed in the retina. Diabetic retinopathy begins with hemorrhages in the blood vessels around the retina (pictured above…
Fig. 11.1 Normal electroretinogram (ERG) Tracings. The a-wave and b-wave are noted where applicable Safety Concerns The normal human eye is generally considered an immune-privileged organ, but one of the…
2. Schaffler A, Buchler C (2007) Concise review: adipose tissue-derived stromal cells–basic and clinical implications for novel cell-based therapies. Stem Cells 25(4):818–827PubMedCrossRef 3. Pittenger MF, Mackay AM, Beck SC et…
Fig. 10.1 Zinc Finger Nucleases introduce site-specific DNA double strand break and the damaged gene is replaced by homologous recombination containing desired gene and a selective marker To date, gene…
Fig. 4.1 Diagrammatic summary of a three-step procedure to differentiate human ES cells into lens progenitor-like cells and lentoid bodies. (a) Diagram of three steps: noggin treatment (days 0–6), BMP4/BMP7/FGF2…
