Reproducibility of Circumpapillary Retinal Nerve Fiber Layer Measurements Using Handheld Optical Coherence Tomography in Sedated Children

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Reproducibility of Circumpapillary Retinal Nerve Fiber Layer Measurements Using Handheld Optical Coherence Tomography in Sedated Children

Purpose To determine the intra- and intervisit reproducibility of circumpapillary retinal nerve fiber layer (RNFL) measures using handheld optical coherence tomography (OCT) in sedated children. Design Prospective cross-sectional and longitudinal…

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The Incidence of Neovascular Subtypes in Newly Diagnosed Neovascular Age-Related Macular Degeneration

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on The Incidence of Neovascular Subtypes in Newly Diagnosed Neovascular Age-Related Macular Degeneration

Purpose To determine the frequency of neovascularization subtypes as determined by fluorescein angiography (FA) alone vs FA and optical coherence tomography (OCT) grading in age-related macular degeneration (AMD). Design Retrospective…

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Optical Coherence Tomography–Based Measurement of Drusen Load Predicts Development of Advanced Age-Related Macular Degeneration

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Optical Coherence Tomography–Based Measurement of Drusen Load Predicts Development of Advanced Age-Related Macular Degeneration

Purpose To determine whether baseline drusen load, as measured using spectral-domain optical coherence tomography (SD OCT), is a useful predictor of development of advanced age-related macular degeneration (AMD). Design Retrospective cohort…

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Study of Subretinal Exudation and Consequent Changes in Acute Central Serous Chorioretinopathy by Optical Coherence Tomography

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Study of Subretinal Exudation and Consequent Changes in Acute Central Serous Chorioretinopathy by Optical Coherence Tomography

Purpose To investigate the characteristics of subretinal exudation and consequent morphologic changes in acute central serous chorioretinopathy (CSC) using spectral-domain optical coherence tomography (OCT). Design Prospective, observational, cross-sectional case series….

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Serum and Plasma Vascular Endothelial Growth Factor Concentrations Before and After Intravitreal Injection of Aflibercept or Ranibizumab for Age-Related Macular Degeneration

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Serum and Plasma Vascular Endothelial Growth Factor Concentrations Before and After Intravitreal Injection of Aflibercept or Ranibizumab for Age-Related Macular Degeneration

Purpose To evaluate serum and plasma vascular endothelial growth factor (VEGF) concentrations in neovascular age-related macular degeneration patients treated bimonthly with an intravitreal injection of aflibercept or ranibizumab. Design Prospective,…

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Treatment of Exudative Age-Related Macular Degeneration with a Designed Ankyrin Repeat Protein that Binds Vascular Endothelial Growth Factor: a Phase I/II Study

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Treatment of Exudative Age-Related Macular Degeneration with a Designed Ankyrin Repeat Protein that Binds Vascular Endothelial Growth Factor: a Phase I/II Study

Purpose To evaluate the safety, tolerability and bioactivity of ascending doses of MP0112, a designed ankyrin repeat protein (DARPin) that binds with high affinity to vascular endothelial growth factor-A (VEGF-A),…

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