Purpose To evaluate the ocular and systemic safety and systemic absorption of AR-13324 in normotensive, healthy volunteers. Design Open-label, noncomparative, single-arm phase 1 clinical trial. Methods setting : Phase 1…
We read with interest the article entitled “Choroidal Thickness in Nonarteritic Anterior Ischemic Optic Neuropathy,” by Schuster and associates. The authors have investigated the choroidal thicknesses (CT) in patients who…
Purpose To investigate the ocular and neurologic manifestations, and to identify the causative mutation in a family with an excavated optic disc anomaly, high myopia, enlarged axial lengths, and abnormal…
Purpose To examine the usefulness of fluorescein angiography (FA) in identifying the macular center and diagnosis of zone in patients with retinopathy of prematurity (ROP). Design Validity and reliability analysis…
Purpose To determine whether the highly reflective vertical lines seen in spectral-domain optical coherence tomographic (SD OCT) images, which we have termed track lines , after resolution of macular edema…
Purpose To investigate whether long-term protection from light exposure affects the rate of disease progression in patients with autosomal recessive Stargardt disease (STGD1), measured using fundus autofluorescence imaging. Design Longitudinal,…
Purpose To investigate the correlation between aqueous flare values and central visual function in patients with retinitis pigmentosa (RP). Design Retrospective, observational case series. Methods We retrospectively studied 160 patients…
Purpose To investigate variables associated with myopic progression despite treatment in the Atropine in the Treatment of Myopia Study. Design Retrospective cohort study. Methods Two hundred of 400 children were…
Purpose To develop a classification and grading system for myopic maculopathy. Design Development and evaluation of a classification system for myopic maculopathy based on observational case series. Methods A comprehensive…
Purpose To characterize spontaneous dislocation of the fluocinolone acetonide sustained release implant (Retisert; Bausch & Lomb) drug pellet from its strut. Design Retrospective, observational case series. Methods The medical records…
