Purpose To evaluate endothelial changes after excimer laser-assisted lamellar keratoplasty. Design Retrospective, interventional case series. Methods Seven eyes of 7 keratoconus patients were evaluated for 1 year after pachymetry-guided lamellar…
Purpose Glaucoma accounts for more than 11% of all cases of blindness in the United States, but there have been few studies of economic impact. We examine incremental cost of…
Purpose To report a surgical technique for aqueous misdirection refractory to medical treatment consisting of combined pars plana vitrectomy, hyaloido-zonulectomy, and peripheral iridectomy. Design Noncomparative case series. Methods The charts…
Purpose To compare the efficacy and safety of laser peripheral iridotomy with or without laser peripheral iridoplasty in the treatment of eyes with synechial primary angle-closure or primary angle-closure glaucoma….
Purpose To evaluate the integrity of the photoreceptor inner segment/outer segment (IS/OS) junction using spectral-domain optical coherence tomography (SD OCT) in patients with diabetic macular edema and to correlate the…
Purpose To examine the prevalence of macular telangiectasia type 2 and lesions characterizing it. Design Population-based cohort study. Methods setting: City and township of Beaver Dam, 1988-1990. study population: A…
Purpose To compare the efficacy of photodynamic therapy (PDT) with or without intravitreal bevacizumab injection for polypoidal choroidal vasculopathy. Design Retrospective, comparative, interventional case series. Methods We included 146 eyes…
Purpose To investigate the relationship between known risk factors for age-related macular degeneration (AMD) progression and foveolar choroidal circulation in eyes with nonexudative AMD. Design Cross-sectional study of nonexudative AMD….
Purpose To assess the safety, tolerability, pharmacokinetics, and dose-limiting toxicity of single intravitreal injection of Sirna-027, a small interfering RNA targeting vascular endothelial growth factor receptor-1, in patients with choroidal…
Purpose To evaluate status of the external limiting membrane (ELM) as a contributor of visual acuity (VA) in age-related macular degeneration (AMD). Design Hospital-based, cross-sectional study. Methods We retrospectively reviewed…
