Viral gene Viral life cycle Transformation and oncogenesis Immune modulation E1 DNA helicase activity. Regulates viral gene transcription E2 Regulates early gene promoter Knockout due to integration of viral genome…
Fig. 10.1 Tracheal papilloma at the distal tip of the indwelling tracheostomy tube One study noted that the right proximal bronchus was consistently more severely affected than the left (Blackledge…
Study Design Cohort Outcomes Bevacizumab Mohr et al. (2014) Case series Intravenous: 5–15 mg/kg per dose q 2–3 weeks initially, then increase interval N = 5 4 adults 1 child,…
Fig. 6.1 Clinical score, modified from the Derkay-Coltrera RRP staging /severity score (Derkay et al. 1998) Unfortunately, there does not currently exist a validated, disease-specific tool for measuring HRQOL in…
Gardasil Gardasil 9 Cervarix Gender Females and males in the USA Females and males in the USA Females Age (years) 9–26 Females 9–26 and males 9–21 9–25 Recommended age…
Fig. 2.1 Global reported rates of incidence and prevalence of JoRRP. Rates are per 100,000 children 2.1.1 Africa Estimates of incidence and prevalence for JoRRP have been reported for the…
Study Type of study Study period Onset (age) Incidence per 100,000 persons Prevalence per 100,000 persons Country/study population Lindeberg and Elbrond (1990) Population-based registry 1968–1984 Juvenile (<20 years) 0.362 – Denmark/Funen…
© Springer International Publishing AG 2018Paolo Campisi (ed.)Recurrent Respiratory Papillomatosishttps://doi.org/10.1007/978-3-319-63823-2_5 5. Human Papillomavirus Vaccination: Making Sense of the Public Controversy Talía Malagón1 and Eduardo L. Franco1 (1) Division of Cancer Epidemiology, McGill University, 5100 Maisonneuve Blvd West,…
Fig. 12.1 Fulminant gram-negative neonatal endogenous endophthalmitis. Note periorbital edema (top left), conjunctival chemosis, corneal edema, and exudates in anterior chamber (top right). Ultrasonography shows vitreous echoes, choroidal thickening, and…
Fig. 7.1 Presumed non-infective endophthalmitis presented with corneal oedema, hypopyon and fibrin with normal ultrasonography and no adnexal inflammation. It needs close observation over the next 6–8 h with topical corticosteroids…
