Molecular Genetics and Pharmacogenomics of the Glaucomas This chapter introduces the reader to the shift from a “single gene, rare disease” concept to a “complex and multiple gene disease” model….

Glaucomas Associated with Intraocular Hemorrhage Intraocular hemorrhage is most commonly caused by trauma or surgery. Hyphemas may occur spontaneously in association with several ocular disorders, most of which are discussed…

Prostaglandins and Hypotensive Lipids The prostaglandins, thromboxanes, and leukotrienes are eicosanoids, which are metabolic products of 20-carbon arachidonic acid (Fig. 28.1). After the prostaglandins are synthesized, they are released and…

The Glaucoma Suspect: When to Treat? Distinguishing healthy persons in the general population from those at considerably increased risk for chronic open-angle glaucoma (COAG) is important because patients in the…

Principles of Incisional Surgery A division between laser surgery for glaucoma and the more traditional glaucoma operations is becoming more and more artificial. The latter surgical category was originally distinguished…

Anatomic Principles of Glaucoma Surgery All laser and incisional surgical procedures for glaucoma are designed to reduce the intraocular pressure (IOP) by increasing the rate of aqueous humor outflow or…