Purpose To describe a patient with 2 ipsilateral supernumerary caruncles and to determine if they are predictive of associated abnormalities. Design Retrospective and interventional clinicopathologic study with a critical review…

Purpose To determine whether implantation of an aspherical intraocular lens (IOL) results in reduced ocular aberrations and improved contrast sensitivity after cataract surgery without critical reduction of depth of focus….

Facing an enormous influx of information from medical research, clinicians need to differentiate robust study findings from spurious ones and to decide which results they can use with high confidence…

In the 1950s and ’60s, a doctoral student in biostatistics could be reasonably expected to acquire a fairly sophisticated knowledge of the whole field before completing the doctoral dissertation. This…

Although von Graefe described some of the clinical aspects of “relapsing idiopathic detachment of the macula” as early as 1866, it was more than 100 years later that Maumenee, using…

Most medical journals do not have a mechanism for producing well-written evidence-based medicine on a measured monthly basis. Some published articles are poorly written and some have few usable clinical…

Purpose To assess retinal nerve fiber layer (RNFL) and macular thickness using optical coherence tomography (OCT) on HIV-infected patients without ocular manifestations and to correlate these findings with frequency-doubling technology…