Purpose To evaluate the effectiveness of artificial tears and corticosteroids on mitigating the acute ocular surface response to low-humidity environments. Design Single-group, crossover clinical trial. Methods Twenty subjects with aqueous…
Purpose To evaluate the diagnostic value of tear osmolarity and several ocular surface parameters in screening for ocular surface alterations in ocular graft-vs-host disease (GVHD) patients. Design Case-control study. Methods…
Six decades ago, as the implications of the double helix were being pondered over, another basic discovery in medical genetics was quietly made. Since the 1920s, the standard chromosome count…
Purpose To perform a quantitative trait locus (QTL) analysis and evaluate whether a locus between SIX1 and SIX6 is associated with retinal nerve fiber layer (RNFL) thickness in individuals of…
Purpose To evaluate the relationship between rates of change on frequency doubling technology (FDT) perimetry and longitudinal changes in quality of life (QoL) of glaucoma patients. Design Prospective observational cohort…
Purpose To examine the relationship of choroidal thickness with axial length (AL) and myopia in young adult eyes in the ethnically diverse Correction of Myopia Evaluation Trial (COMET) cohort. Design…
Purpose To investigate the thickness and variation profiles of 8 intraretinal layers in myopia. Design Prospective cross-sectional study. Methods Young subjects with spherical equivalents ranging from +0.50 to −10.25 diopters and good…
Purpose To investigate long-term changes in subfoveal choroidal thickness (SCT) after photodynamic therapy (PDT) and their relationship with chronic central serous chorioretinopathy (CSC) recurrence. Design Retrospective, observational, comparative case series….
Purpose To characterize anatomic and visual outcomes in patients with full-thickness macular hole (FTMH) at baseline in ocriplasmin phase 3 clinical trials, focusing on the relationship between resolution of vitreomacular…
Purpose To estimate incidence of age-related macular degeneration (AMD) by subtype in American whites aged ≥50 years. Design Systematic review and meta-analysis. Methods setting : Prospective cohort studies of AMD…
