52 Coats Disease
From Gomez Morales A. Coats’ disease. Natural history and results of treatment. Am J Ophthalmol 1965;60:855–864; Shields JA, Shields CL, Honavar SG, et al. Classification and management of Coats’ disease:…
24 Gene Therapy and Pharmacology
Listed are the diseases, the genetic defects, and the gene therapy strategies under consideration. ABCA4, ATP-binding cassette transporter cassette A member 4 gene; AR, autosomal recessive; NA, not applicable; AD,…
43 Oxidative Stress and Signaling Pathways Involved in Developmental and Aberrant Angiogenesis Relating to Retinopathy of Prematurity
FIGURE 43.1 Factors contribute to the development of ROP. Low serum insulin-like growth factor-1 (IGF-1) and its binding protein 3 IGFBP3 derived from preterm birth lead to impaired retinal vascular development….
1 Embryology of the Retina and Developmental Disorders
RPE, retinal pigment epithelium. TABLE 1.2 Time line of retinal development: organogenesis RPE, retinal pigment epithelium. TABLE 1.3 Time line of retinal development: differentiation IRBP, interstitial retinol-binding protein. FIGURE 1.1 Four-week-old…
31 Tumors in Infants and Children
FIGURE 31.1 The orange-red elevated mass demonstrates the characteristic appearance of choroidal hemangiomas. Most circumscribed choroidal hemangiomas are located in the postequatorial fundus (5,8). The posterior margin of the majority of…
