6 Choroidal Vascular Development

Oct 2, 2016 by in OPHTHALMOLOGY Comments Off on 6 Choroidal Vascular Development

FIGURE 6.1 Cross-sections of 6.5 WG fetal choroid demonstrate hemovasculogenesis (A–F). Erythroblasts (bright pink cytoplasm) in the CC layer can form solid cord-like structures (double arrow) without a lumen (A). Erythroblasts…

read more

52 Coats Disease

Oct 2, 2016 by in OPHTHALMOLOGY Comments Off on 52 Coats Disease

From Gomez Morales A. Coats’ disease. Natural history and results of treatment. Am J Ophthalmol 1965;60:855–864; Shields JA, Shields CL, Honavar SG, et al. Classification and management of Coats’ disease:…

read more

24 Gene Therapy and Pharmacology

Oct 2, 2016 by in OPHTHALMOLOGY Comments Off on 24 Gene Therapy and Pharmacology

Listed are the diseases, the genetic defects, and the gene therapy strategies under consideration. ABCA4, ATP-binding cassette transporter cassette A member 4 gene; AR, autosomal recessive; NA, not applicable; AD,…

read more

43 Oxidative Stress and Signaling Pathways Involved in Developmental and Aberrant Angiogenesis Relating to Retinopathy of Prematurity

Oct 2, 2016 by in OPHTHALMOLOGY Comments Off on 43 Oxidative Stress and Signaling Pathways Involved in Developmental and Aberrant Angiogenesis Relating to Retinopathy of Prematurity

FIGURE 43.1 Factors contribute to the development of ROP. Low serum insulin-like growth factor-1 (IGF-1) and its binding protein 3 IGFBP3 derived from preterm birth lead to impaired retinal vascular development….

read more

1 Embryology of the Retina and Developmental Disorders

Oct 2, 2016 by in OPHTHALMOLOGY Comments Off on 1 Embryology of the Retina and Developmental Disorders

RPE, retinal pigment epithelium. TABLE 1.2 Time line of retinal development: organogenesis RPE, retinal pigment epithelium. TABLE 1.3 Time line of retinal development: differentiation IRBP, interstitial retinol-binding protein. FIGURE 1.1 Four-week-old…

read more
Get Clinical Tree app for offline access