Safety Assessment and Power Analyses in Published Anti–Vascular Endothelial Growth Factor Randomized Controlled Trials

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Safety Assessment and Power Analyses in Published Anti–Vascular Endothelial Growth Factor Randomized Controlled Trials

Purpose To investigate a certain set of methodological limitations in published anti–vascular endothelial growth factor (VEGF) randomized controlled trials (RCTs). Design Descriptive methodological study. Methods We did a PubMed search…

read more

Analysis of Intraocular Lens Biofilms and Fluids After Long-Term Uncomplicated Cataract Surgery

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Analysis of Intraocular Lens Biofilms and Fluids After Long-Term Uncomplicated Cataract Surgery

Purpose Postoperative endophthalmitis is a potentially sight-threatening complication of cataract surgery. However, the pathophysiological mechanisms are not completely understood. We sought to study and evaluate the intraocular environment (aqueous and…

read more

Visual Field Progression Pattern Associated With Optic Disc Tilt Morphology in Myopic Open-Angle Glaucoma

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Visual Field Progression Pattern Associated With Optic Disc Tilt Morphology in Myopic Open-Angle Glaucoma

Purpose To understand the long-term characteristics of visual field (VF) progression in myopic open-angle glaucoma (OAG) according to the morphology of optic disc tilt. Design Retrospective, comparative, longitudinal cohort study….

read more

Unilateral BEST1-Associated Retinopathy

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Unilateral BEST1-Associated Retinopathy

Purpose To describe a series of patients with molecularly confirmed mutation in BEST1 causing Best disease but with unilateral clinical manifestation. Design Retrospective observational case series. Methods Setting : Moorfields…

read more

Automated Quantitative Analysis of Retinal Microvasculature in Normal Eyes on Optical Coherence Tomography Angiography

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Automated Quantitative Analysis of Retinal Microvasculature in Normal Eyes on Optical Coherence Tomography Angiography

Purpose To describe a new automated quantitative technique for displaying and analyzing macular vascular perfusion using optical coherence tomography angiography (OCT-A) and to determine a normative data set, which might…

read more

Immunosuppressive Drug Discontinuation in Noninfectious Uveitis From Real-Life Clinical Practice: A Survival Analysis

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Immunosuppressive Drug Discontinuation in Noninfectious Uveitis From Real-Life Clinical Practice: A Survival Analysis

Purpose To assess in uveitis patients the rate of immunosuppressive drug (ISD) discontinuation in real-life clinical practice, comparing this rate among ISDs. Design Longitudinal retrospective cohort study. Methods We included…

read more

Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A Look Both Home and Abroad

Jan 5, 2017 by in OPHTHALMOLOGY Comments Off on Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A Look Both Home and Abroad

Exudative retinal diseases, including age-related macular degeneration (AMD), diabetic retinopathy, and venous occlusive disease, are major contributors to vision loss globally. Fortunately, many ocular-specific treatments have been developed over the…

read more
Get Clinical Tree app for offline access