Purpose To determine if short-term Age-Related Eye Disease Study (AREDS) antioxidant and zinc supplementation affects biomarkers of oxidative stress, possibly serving as a predictor of their efficacy. Design Prospective interventional…
Purpose To describe new affected individuals of Franceschetti’s original pedigree of hereditary recurrent erosion and to classify a unique entity called Franceschetti corneal dystrophy. Design Observational case series. Methods Slit-lamp…
Purpose To compare the outcomes of trabeculectomy surgery after Descemet stripping automated endothelial keratoplasty (DSAEK) to penetrating keratoplasty (PK). Design Retrospective case-control study. Methods Patients within an institutional setting who…
Purpose To evaluate the impact of ocular surface symptoms on quality of life in a veteran population receiving eye care services. Design Cross-sectional survey study. Methods setting: Miami Veterans Affairs…
Purpose To determine the clinical and ultrasound biomicroscopy (UBM) features associated with growth in iris melanocytic lesions. Study Design Retrospective case series analysis. Methods We included all iris melanocytic lesions…
Purpose To investigate the efficacy and safety of an investigational integrin antagonist (SAR 1118) ophthalmic solution compared to placebo (vehicle) in subjects with dry eye disease. Design Multicenter, prospective, double-masked,…
Purpose To investigate the clinical and genetic features of late-onset Fuchs corneal dystrophy (FCD) on Tangier, an island in the Chesapeake Bay with an isolated population of approximately 500 individuals….
Carl Koller (1837-1944) became known in Vienna at the age of 26 when he first appreciated the usefulness of cocaine as a local anesthetic in ophthalmology. He nonetheless decided that…
Purpose To evaluate the safety and possible efficacy of subconjunctival sirolimus for the treatment of chronic active anterior uveitis. Design Prospective, nonrandomized, open-label clinical trial. Methods This single-center pilot trial…
Purpose To evaluate the efficacy of quantitative real-time polymerase chain reaction (qPCR) in the diagnosis of postoperative bacterial endophthalmitis among patients who underwent cataract surgery at a tertiary care center….
