General Cardiac CNS Renal GI Decreased bone density Bradycardia Fatigue Nephrocalcinosis Constipation Anorexia Shortened QT interval Hypotonia/weakness Nephrolithiasis Nausea/vomiting Weight loss Prolonged PR interval Seizure Urolithiasis Pancreatitis Pruritus Arrhythmias Coma…
Fig. 18.1 Preoperative imaging studies in candidate for minimally invasive, video-assisted parthyroidectomy. Early (a) and delayed (b) Tc-99m-sestamibi and SPECT-CT images (c) suggesting a parathyroid lesion posterior to the inferior…
PTH1–84 20 % (Range 5–30 %) N-terminal fragments 2 % (Range 0–5 %) C-terminal fragments 80 % (Range 75–95 %) PTH with an N-terminal structure (or the first 34 amino…
Fig. 15.1 Left superior parathyroid adenoma. A-25 year-old African-American female presented with renal disease and prior removal of three parathyroid glands due to hyperparathyroidism. Her post-surgical serum calcium and PTH…
Fig. 3.1 Formation of the pharyngeal pouches and their corresponding derivatives. From [2]. PA pharyngeal arch These endodermal outpockets contact the surface ectoderm at precise sites along the anterior–posterior axis…
(1) Division of Endocrinology and Metabolism, McMaster University, 1280 Main St W, Hamilton, ON, Canada, L8S 4L8 (2) Clinical Medicine, Divisions Endocrinology and Metabolism and Geriatrics, McMaster University, 1280 Main…
Fig. 6.1 Germline mutations in the MEN 1 gene. These mutations are distributed within the nine coding exons of the gene and include missense, nonsense, frameshift, etc. Above the depiction…
Fig. 34.1 Intraoperative defatting of the parathyroid tissue Fig. 34.2 Fragmentation of the parathyroid tissue Fig. 34.3 Transportation to the laboratory in a tube with Dulbecco’s modified Eagle medium In…
Fig. 19.1 Preoperative imaging for a patient undergoing unilateral parathyroid surgery. Early (a) and delayed (b) Tc-99m-sestamibi scans showed slightly more persistent uptake in the right inferior central neck. These…
Fig. 28.1 HRpQCT image of the distal radius; separated according to cortical vs. trabecular components [48] Fig. 28.2 Representative HRpQCT images of the distal radius of PHPT (a) and control…
