Ocular Developmental Anomalies Scott E. Olitsky Leonard B. Nelson The clinical identification of an ocular developmental anomaly should stimulate curiosity concerning the etiology and pathogenesis of the condition. Etiology refers…
Pathology of the Optic Nerve Diva R. Salomão Caterina Giannini Introduction The optic nerve, second cranial nerve, is approximately 50 mm long. It extends from the optic nerve disc inside…
Glaucoma Genetics Michael J. Pro MD Mauricio Pons MD Introduction It is not hyperbole to say that discoveries in genetics will lead to a revolution in medical care. Gene therapy…
Inborn Errors of Metabolism Donald P. Sauberan MD Scott E. Olitsky MD Leonard Nelson MD An inborn error of metabolism is a clinical disorder caused by a genetic inability to…
Basics of Inheritance Arlene V. Drack Most physicians think of inherited eye diseases as “zebras”—rare, one of a kind disorders seldom encountered in a typical practice. In fact, most patients…
Principles of Genealogical Research and Practical Applications to Eye Disease Tara Uhler Tamara Vrabec Arcilee Frost Larry A. Donoso Introduction Background/History The study of ancestry or families, genealogy, is a…
Pathology of the Retina Gavin W. Roddy Robert H. Rosa Jr. CONGENITAL ABNORMALITIES Retinal Coloboma Colobomas arise from an incomplete fusion of the two sides of the optic cup afer…
Heredity of Strabismus Sylvia R. Kodsi Steven E. Rubin Mary A. O’Hara Leonard B. Nelson Generations of ophthalmologists have noted that strabismus “tends to run in families.” Hippocrates first commented…
Clinicopathologic Correlates in Orbital Disease Zeynel A. Karcioglu Of all essential human senses, vision is the most important. The eye, organ of vision, should be well protected and supported functionally…
Chromosomes: Structure, Function, and Clinical Syndromes Brian J.R. Forbes Leonard B. Nelson Sanger’s demonstration in 1953 that proteins are unique linear arrays of amino acids and the suggestion by Watson…
