Purpose To characterize anatomic and visual outcomes in patients with full-thickness macular hole (FTMH) at baseline in ocriplasmin phase 3 clinical trials, focusing on the relationship between resolution of vitreomacular…
Purpose To estimate incidence of age-related macular degeneration (AMD) by subtype in American whites aged ≥50 years. Design Systematic review and meta-analysis. Methods setting : Prospective cohort studies of AMD…
Purpose To analyze the long-term dynamic healing process of outer retinal changes for 1 year in patients who underwent a standard vitrectomy procedure for idiopathic macular hole (MH) repair. Design…
Purpose To evaluate how optical coherence tomography (OCT) angiography depicts clinical fundus findings in patients with diabetic retinopathy (DR). Design Prospective study evaluating imaging technology. Methods Forty-seven eyes of 25…
Purpose To investigate the short-term effects of intravitreal ranibizumab on retinal vessel functionality in patients with retinal vein occlusion (RVO). Design Prospective, interventional case series. Methods We enrolled 11 eyes…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To evaluate the spectrum of retinal diseases that can demonstrate paracentral acute middle maculopathy and isolated ischemia of the intermediate and deep capillary plexus. Design Retrospective, multicenter, observational case…
Purpose To investigate the vascular appearance of choroidal neovascularization (CNV) treated with recurrent intravitreous anti–vascular endothelial growth factor (VEGF) injections, which have been proposed to cause transient vascular normalization along…
The history of medicine is characterized by discovery, subclassification, reorganization, and bifurcation of physiological concepts or pathologic entities, driven by advances in investigative technologies or by recognition of clinical details…
Key to the practice of evidence- and outcome-based medicine is data that are trustworthy. Sponsors of novel medical therapies are required to provide data from well-controlled studies to support their…
