Purpose To evaluate the increase in tear fluid volume induced by 3% diquafosol ophthalmic solution in normal human eyes. Design Prospective, randomized, double-masked, comparative study. Methods Twenty healthy adults (17…
Purpose To determine the long-term cost-effectiveness of osteo-odonto keratoprosthesis (OOKP) relative to no treatment among patients with end-stage corneal and ocular surface diseases in Singapore. Design Cost-effectiveness analysis based on…
Purpose To evaluate the correlation between changes in tear osmolarity, symptoms, and corneal fluorescein staining in patients with dry eye disease (DED). Design Retrospective, clinic-based cohort study. Methods In this…
Purpose To evaluate in vivo epithelial thickness in dry eye by anterior segment optical coherence tomography. Design Observational, retrospective case-control study. Methods Two age-matched groups of female subjects, 70 eyes each,…
Purpose To determine the 24-hour effects of travoprost with sofZia on intraocular pressure (IOP) and ocular perfusion pressure as well as the endurance of IOP lowering after last dosing. Design…
Purpose To determine risk factors and clinical signs that may differentiate between bacterial, fungal, and acanthamoeba keratitis among patients presenting with presumed infectious keratitis. Design Hospital-based cross-sectional study. Methods We…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To report the endothelial cell loss and clinical outcomes in Descemet stripping automated endothelial keratoplasty (DSAEK) with internationally shipped, precut donor corneas. Design Retrospective analysis of a noncomparative case…
Purpose To summarize the epidemiology of pathologic myopia and myopic choroidal neovascularization (CNV) and their impact on vision. Design Systematic literature review of all English-language studies evaluating the epidemiology and…
Purpose To explore the relationship between the visual field index (VFI) and the visual field mean deviation (MD) in glaucoma patients with moderately advanced perimetric damage and to identify the…
