The First Anti-VEGF Therapy: Pegaptanib Sodium
37 The First Anti-VEGF Therapy: Pegaptanib Sodium Anthony P. Adamis INTRODUCTION Until recently, the treatment of ocular neovascular diseases such as age-related macular degeneration (AMD), diabetic retinopathy (DR), and…
Pharmacotherapy of Diabetic Retinopathy
20 Pharmacotherapy of Diabetic Retinopathy Yoshihiro Yonekawa Aziz A. Khanifar Donald J. D’Amico R.V. Paul Chan Diabetes mellitus (DM) is a major cause of morbidity and mortality throughout the…
Principles and Techniques of Macular Surgery
15 Principles and Techniques of Macular Surgery Gerardo García-Aguirre Raúl Velez-Montoya Hugo Quiroz-Mercado HISTORY Since its inception in the early sixties (1, 2), vitrectomy procedures have been performed in…
Macular Edema Associated with Aphakia and Pseudophakia
23 Macular Edema Associated with Aphakia and Pseudophakia Hiroko Terasaki INTRODUCTION Cystoid macular edema (CME) is characterized by cystoid spaces in the macular area with perifoveal fluorescein leakage, increased…
Microplasmin and Vitreoretinal Surgery
14 Microplasmin and Vitreoretinal Surgery David T. Goldenberg Anselm Kampik Arnd Gandorfer Michael Trese INTRODUCTION The vitreoretinal interface plays an important role in the pathogenesis of many retinal disorders….
Pathophysiology of the Blood-Retinal Barrier
3 Pathophysiology of the Blood-Retinal Barrier Pablo Carnota Rafael Bueno Monica Rodriguez-Fontal John B. Kerrison INTRODUCTION In order to maintain the unique microenvironment needed for viability and optimal function…