Indications for Reoperative Parathyroidectomy
1990 2002 2008 2013 Serum calcium (mg/dL above upper limit of normal) 1–1.6 1 1 1 Skeletal DEXA z-score less than −2.0 DEXA t-score less than −2.5 at any…
Surgical Techniques and Pearls: The Unsuccessful Reoperation
© Springer International Publishing AG 2018Ralph P. Tufano and Phillip K. Pellitteri (eds.)Reoperative Parathyroid Surgery https://doi.org/10.1007/978-3-319-60723-8_6 6. Surgical Techniques and Pearls: The Unsuccessful Reoperation Jeffrey M. Bumpous1 and Mary Worthen1 (1) Department of Otolaryngology, Head and Neck Surgery…
Contemporary Management of Recurrent Respiratory Papillomatosis in Children
Fig. 8.1 Anatomic representation of laryngeal (a) and respiratory tract (b) epithelium indicating squamociliary junctions at which recurrent respiratory papilloma predilection occurs (Republished with permission from Kashima et al. 1993)…
Contemporary Management of Recurrent Respiratory Papillomatosis in Adults
Fig. 7.1 Procedure setup. (a) Patient is receiving a nebulizer treatment of 3 mL of 4% lidocaine pre-procedure. (b) Patient positioning and procedure room setup. Note the KTP laser machine on…
Human Papillomavirus and Head and Neck Cancer
Fig. 11.1 HPV carcinogenesis process 11.2 HPV+ HNSCC Burden Based on GLOBOCAN 2012 (Ferlay et al. 2015), head and neck cancer accounted for 4.8% of the 14.1 million new cancer…
Advocacy for Recurrent Respiratory Papillomatosis
Hoarseness 590 (80.2%) Breathing disorder 266 (36.1%) Swallowing disorder 130 (17.7%) Voice abnormality 541 (73.5%) Breathing abnormality during exercise 308 (41.8%) Breathing abnormality at rest 234 (31.8%) Active papilloma growth…
Fundamental Biology of Human Papillomaviruses
Viral gene Viral life cycle Transformation and oncogenesis Immune modulation E1 DNA helicase activity. Regulates viral gene transcription E2 Regulates early gene promoter Knockout due to integration of viral genome…
Malignant Transformation and Distal Airway Complications
Fig. 10.1 Tracheal papilloma at the distal tip of the indwelling tracheostomy tube One study noted that the right proximal bronchus was consistently more severely affected than the left (Blackledge…
The Cidofovir Controversy
Study Design Cohort Outcomes Bevacizumab Mohr et al. (2014) Case series Intravenous: 5–15 mg/kg per dose q 2–3 weeks initially, then increase interval N = 5 4 adults 1 child,…
Impact on Quality of Life
Fig. 6.1 Clinical score, modified from the Derkay-Coltrera RRP staging /severity score (Derkay et al. 1998) Unfortunately, there does not currently exist a validated, disease-specific tool for measuring HRQOL in…
