The Role of Fungus in Chronic Rhinosinusitis
Fungus has been cited as an etiologic factor (the etiologic factor?) in chronic rhinosinusitis (CRS), and a vigorous debate has ensued. Initial reports of in vitro observations promoted fungus as…
Superantigens
Superantigens (SAgs) are derived from diverse sources, including bacteria, viruses, and human hepatic tissue. SAgs initially cause lymphocyte activation but then result in clonal deletion and anergy, leading to immune…
Local and Systemic IgE in the Evaluation and Treatment of Allergy
Traditional descriptions of type I hypersensitivity and its manifestations center on systemic immunoglobulin E (IgE)-mediated reactions to inciting antigens. Hence, many current diagnostic and therapeutic measures are based on systemic…
Cilia Dysfunction
Cilia are complex and powerful cellular structures that serve a multitude of functions across many types of organisms. In humans, one of the most critical roles of cilia is defense…
Ten Pearls for Safe Endoscopic Sinus Surgery
Endoscopic sinus surgery is an excellent treatment option in the management of medically refractory chronic rhinosinusitis. Continual refinements in endoscopic technique are simultaneously allowing an expanded range of applications and…
Malpractice Claims in Nasal and Sinus Surgery: A Review of 15 Cases
Otolaryngologists may encounter claims of medical malpractice during the course of their careers. A sample of 15 cases involving patient claims of medical malpractice relating to care delivered for problems…
10 Pearls for Safe Endoscopic Skull Base Surgery
The introduction of the endoscopic endonasal approach for the management of lesions of the skull base has produced a paradigm shift in the way complicated lesions of this complex anatomic…
Medicolegal Issues in Endoscopic Sinus Surgery
Endoscopic sinus surgery is one of the most litigated areas in otolaryngology. Physicians typically receive little education regarding medicolegal issues during training and may find themselves in an unfamiliar territory…
Informed Consent Process and Patient Communication After Complications in Sinus Surgery
Sinonasal surgery has always been a potential source of complications. Most legal suits involving endoscopic sinus surgery alleged lack of informed consent. In this article, the authors discuss what informed…