Purpose To examine the prevalence of macular telangiectasia type 2 and lesions characterizing it. Design Population-based cohort study. Methods setting: City and township of Beaver Dam, 1988-1990. study population: A…
Purpose To compare the efficacy of photodynamic therapy (PDT) with or without intravitreal bevacizumab injection for polypoidal choroidal vasculopathy. Design Retrospective, comparative, interventional case series. Methods We included 146 eyes…
Purpose To investigate the relationship between known risk factors for age-related macular degeneration (AMD) progression and foveolar choroidal circulation in eyes with nonexudative AMD. Design Cross-sectional study of nonexudative AMD….
Purpose To assess the safety, tolerability, pharmacokinetics, and dose-limiting toxicity of single intravitreal injection of Sirna-027, a small interfering RNA targeting vascular endothelial growth factor receptor-1, in patients with choroidal…
Purpose To evaluate status of the external limiting membrane (ELM) as a contributor of visual acuity (VA) in age-related macular degeneration (AMD). Design Hospital-based, cross-sectional study. Methods We retrospectively reviewed…
Purpose To analyze risk factors for postoperative recurrence of fibrovascular tissue in eyes with aggressive posterior retinopathy of prematurity (AP ROP) treated with early vitreous surgery. Design Retrospective, consecutive, observational…
Purpose The course of intermittent exotropia and response to surgery may depend on whether there is underlying monofixation. The purpose of this study was to report the prevalence of sensory…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To evaluate anterior segment complication rates in eyes treated for prethreshold versus threshold retinopathy of prematurity (ROP) and look for potential risk factors. Design Retrospective, observational case series study….
History Cohort studies often are viewed as the gold standard in observational epidemiology, and the first large cohort study was conducted as early as 1913. Wilhelm Weinberg reported in the…
