Outcomes: Recurrence of Disease
Fig. 9.1 Donor keratocytes as a proportion of total keratocytes counted in each of 52 corneal grafts, plotted against graft age. Subset of eight transparent grafts removed due to reasons…
The Penetrating Keratoplasty (PKP): A Century of Success
Early postoperatively with sutures in place: Symmetry of suture positions Homogeneity of suture tension Late postoperatively persisting without sutures: Cut quality Wound configuration (horizontal/vertical) Symmetry of graft placement The low…
Limbal Stem-Cell Expansion and Transplantation
Fig. 16.1 Failure of autologous limbal transplantation with recurrence of corneal conjunctivalization (a). Contralateral donor eye with signs of a large previous limbal harvesting for limbal transplantation (white arrows) and…
National Corneal Transplant Registries
Fig. 10.1 An example of national registry data from the Australian Corneal Graft Registry (http://hdl.handle.net/2328/25860). Long-term survival of penetrating keratoplasty, lamellar keratoplasty and limbal allografts (Reproduced with permission of the…
Mechanical Microkeratomes
Fig. 14.1 Automated lamellar microkeratome 300 μm cut in a patient with granular dystrophy A more recent modified technique of microkeratome-assisted LK consists of removing the anterior lamella from the…
Endothelial Keratoplasty
Indications Contraindications Consideration Fuchs’ dystrophy Significant irreversible central corneal scarring Large iris defects Bullous keratopathy (aphakic or pseudophakic) Keratoconus Aniridia Posterior polymorphous dystrophy Hypotony Glaucoma tubes Iridocorneal endothelial (ICE) syndrome …
Anatomy and Physiology: Considerations in Relation to Transplantation
Fig. 2.1 Light (a) and transmission electron (b–h) micrographs of anatomical corneal layers. (a) Semithin cross section of the cornea showing three cellular layers, i.e., epithelium, stroma with keratocytes, and…
Economic Evaluation of Keratoplasty
Cost consequences analysis Cost-minimization analysis Cost-effectiveness analysis Cost-utility analysis Cost-benefits analysis Cost $ $ $ $ $ Outcomes Many outcomes can be considered Many outcomes can be considered All…
Post-operative Management
Fig. 8.1 Corneal vascularisation with graft failure secondary to graft rejection. Vascularisation of the recipient corneal bed is the most significant single risk factor for graft failure on multivariate analysis…
Decision-Making in Keratoplasty
Vascularization of the recipient stroma Anterior synechiae Previous graft failure due to immunological rejection Previous or ongoing anterior segment inflammation Uncontrolled glaucoma or glaucoma surgery Herpes simplex keratitis Ocular surface…
