Purpose To identify the 23 amino acid profiles in human tear fluids, and to evaluate whether the ocular disease conditions reflect the amino acid profiles. Design Laboratory investigation. Methods We…
Purpose To evaluate the newly developed Ocular Surface Thermographer (TOMEY Corporation) for dry eye screening. Design Prospective, controlled study. Methods We studied 30 eyes of 30 patients diagnosed with dry…
Purpose To evaluate the use of tear osmolarity in the diagnosis of dry eye disease. Design A prospective, observational case series to determine the clinical usefulness of tear osmolarity and…
Purpose To compare intraocular pressure (IOP) measurements obtained using the Goldmann applanation tonometer (GAT; Haag-Streit), the Tono-Pen XL (Reichert, Inc), and the ocular response analyzer (ORA; Reichert Ophthalmic Instruments), and…
Purpose To estimate the expected incremental lifetime cost of treatment of keratoconus compared to the expected cost of the treatment of myopia. Design Cost estimate from the patient’s perspective using…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To evaluate the long-term endothelial cell density (ECD) changes and visual and refractive outcomes after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique in eyes with keratoconus. Design…
Purpose To assess the presence of transforming growth factor-β (TGFβ) pathway markers in the epithelium of keratoconus patient corneas. Design Retrospective, comparative case series of laboratory specimens. Methods Immunohistochemistry results…
Purpose To review the history of indocyanine green (ICG) angiography and to present a personal perspective on its use in the clinical setting today. Design Perspective with literature review and…
The Tube Versus Trabeculectomy (TVT) Study was designed to answer the question of whether instillation of an aqueous drainage device (tube) or a trabeculectomy (trab) should be performed on patients…
