OPHTHALMOLOGY
High Diagnostic Yield of Whole Exome Sequencing in Participants With Retinal Dystrophies in a Clinical Ophthalmology Setting
Purpose To assess the diagnostic yield and the practicality of implementing whole exome sequencing within a clinical ophthalmology setting. Design Evaluation of a diagnostic protocol. Methods setting : Patient participants…
Lamellar Hole–Associated Epiretinal Proliferation in Comparison to Epiretinal Membranes of Macular Pseudoholes
Purpose To compare immunocytochemical and ultrastructural characteristics of “lamellar hole–associated epiretinal proliferation” in lamellar macular holes with “conventional epiretinal membrane” in macular pseudoholes. Design A consecutive observational case series, laboratory…
Strabismus Surgery Reoperation Rates With Adjustable and Conventional Sutures
Purpose To determine the association of strabismus surgery reoperation rates with adjustable or conventional sutures. Design Retrospective cross-sectional study. Methods setting : Review of a large national private insurance database….
Predominantly Cone-System Dysfunction as Rare Form of Retinal Degeneration in Patients With Molecularly Confirmed Bardet-Biedl Syndrome
Purpose To describe a series of patients with Bardet-Biedl syndrome (BBS) and predominantly retinal cone dysfunction, a previously only rarely reported association. Design Retrospective observational case series. Methods Seven patients…
Risk Factors Predictive of Endogenous Endophthalmitis Among Hospitalized Patients With Hematogenous Infections in the United States
We read with great interest the article by Vaziri and associates describing risk factors predictive of endogenous endophthalmitis among hospitalized patients with hematogenous infections in the United States. In their…
Choroidal Maps in Different Types of Macular Edema in Branch Retinal Vein Occlusion Using Swept-Source Optical Coherence Tomography
Purpose To compare choroidal thickness maps of different types of macular edema secondary to branch retinal vein occlusion (BRVO) using swept-source optical coherence tomography (SS OCT). Design Retrospective cross-sectional study….
Pro-Permeability Factors After Dexamethasone Implant in Retinal Vein Occlusion; the Ozurdex for Retinal Vein Occlusion (ORVO) Study
Purpose To correlate aqueous vasoactive protein changes with macular edema after dexamethasone implant in retinal vein occlusion (RVO). Design Prospective, interventional case series. Methods Twenty-three central RVO (CRVO) and 17…
Identification of Drusen Characteristics in Age-Related Macular Degeneration by Polarization-Sensitive Optical Coherence Tomography
Purpose To describe qualitative characteristics of drusen in eyes with nonadvanced age-related macular degeneration (AMD) using polarization-sensitive optical coherence tomography (OCT). Design Cross-sectional study. Methods Twenty-five eyes of 25 patients…
Fundus Autofluorescence Changes After Ranibizumab Treatment for Subfoveal Choroidal Neovascularization Secondary to Pathologic Myopia
Purpose To describe fundus autofluorescence (FAF) patterns of myopic choroidal neovascularization (CNV) treated with intravitreal ranibizumab and their correlation with visual acuity. Design Prospective interventional case series. Methods Twenty-seven eyes…
