Purpose To identify the optimal dose of a novel Rho kinase inhibitor, K-115, by assessing dose dependency of the intraocular pressure (IOP)-lowering effects and the safety in patients with primary…
Purpose To validate and evaluate the reliability of retinal vessel diameter measurements by optical coherence tomography (OCT). The effects of age and hypertension on vessel diameter were also examined. Design…
Purpose To describe a series of patients with geographic atrophy independent of choroidal neovascularization (CNV) in pseudoxanthoma elasticum and to report progression over time. Design Retrospective observational case series. Methods…
Purpose To investigate the predictive factors for diabetic macular ischemia progression through the analysis of fluorescein angiography (FA) parameters. Design Retrospective, longitudinal study. Methods Data were collected from 79 eyes…
Purpose To determine the percentage of ranibizumab-treated patients with retinal vein occlusion (RVO) who had resolution of edema for at least 6 months after the last injection, along with factors and…
Purpose To study the prevalence and 3-dimensional (3-D) tomographic features of focal choroidal excavations in eyes with central serous chorioretinopathy (CSC) using swept-source optical coherence tomography (OCT). Design Prospective, cross-sectional…
Purpose To evaluate changes in contrast sensitivity after surgery for macula-on rhegmatogenous retinal detachment (RRD). Design Prospective, interventional, consecutive, case-control study. Methods This study included 84 eyes of 84 patients…
Purpose To evaluate long-term visual outcome and investigate the prognostic factors after anti–vascular endothelial growth factor (VEGF) therapy for polypoidal choroidal vasculopathy (PCV). Design Retrospective study. Methods Analyses were done…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To estimate and compare the costs of scleral buckle (SB) and pars plana vitrectomy (PPV) for treatment of rhegmatogenous retinal detachment (RRD). Design Cost analysis based on published prospective…
