PURPOSE To generate a prognostic model to predict keratoconus progression to corneal crosslinking (CXL). DESIGN Retrospective cohort study. METHODS We recruited 5025 patients (9341 eyes) with early keratoconus between January…

Purpose To report on the safety of the first 5 cohorts of a gene therapy trial using recombinant equine infectious anemia virus expressing ABCA4 (EIAV-ABCA4) in adults with Stargardt dystrophy…

Purpose To assess the long-term continuous anatomical and functional healing process of a super-large full-thickness macular hole (FTMH) after internal limiting membrane (ILM) filling and air tamponade. Design Prospective, interventional…

PURPOSE The proportions of individuals who are underrepresented in medicine (URiM) in ophthalmology lag behind their proportions within the US population. Diversity trends have been studied in other specialties, but…

Purpose To summarize key findings from a Cochrane systematic review of the effectiveness and safety of topical pharmacologic interventions compared with active control or placebo for epidemic keratoconjunctivitis (EKC). Design Systematic…

Purpose To compare progression of myopia and refractive error in former premature infants with retinopathy of prematurity (ROP) treated using intravitreal bevacizumab (IVB) or laser. Design Retrospective clinical cohort study….

Purpose To report the therapeutic efficacy of integrating neoadjuvant chemotherapy with conventional bimodal therapies for lacrimal gland adenoid cystic carcinoma by providing an additional 8 years of follow-up data on…

Highlights • Total corneal astigmatism (TCA) measurements and predicted refractive astigmatism by the Barrett toric calculator are not interchangeable. • TCA alone may not serve as an adequate reference for…

Purpose To identify the risk factors associated with failure of tube shunt surgery. Design Pooled analysis of 3 prospective multicenter, randomized clinical trials. Methods A total of 621 patients with…