OPHTHALMOLOGY

Effects of Optic Nerve Head Structures on Retinal Nerve Fiber Layer Defects in Primary Open Angle Glaucoma Eyes: Analyses Using Retinal Optical Texture Analysis

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Effects of Optic Nerve Head Structures on Retinal Nerve Fiber Layer Defects in Primary Open Angle Glaucoma Eyes: Analyses Using Retinal Optical Texture Analysis
Purpose To elucidate associations between optic nerve head (ONH) structures and the retinal nerve fiber layer optical texture analysis (ROTA)–detected retinal nerve fiber layer defects (RNFLDs) in primary open angle…
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Progression in X-Linked Retinoschisis: A Longitudinal Study Defining Quantitative Biomarkers and Their Implications for Gene Therapy

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Progression in X-Linked Retinoschisis: A Longitudinal Study Defining Quantitative Biomarkers and Their Implications for Gene Therapy
Purpose To delineate age-related changes in visual, structural, and electrophysiologic measures in X-linked retinoschisis (XLRS) and to assess automated cyst-cavity volume (CCV) as a quantitative biomarker. Design Single-center mixed retrospective-prospective…
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Assessing the Fragility of Statistically Significant Outcomes in Randomized Controlled Trials of Minimally Invasive Glaucoma Surgery (MIGS)

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Assessing the Fragility of Statistically Significant Outcomes in Randomized Controlled Trials of Minimally Invasive Glaucoma Surgery (MIGS)
Topic Minimally invasive glaucoma surgery (MIGS) has been widely adopted as a surgical option for glaucoma, yet concerns remain regarding the robustness of the evidence supporting many procedures. The fragility…
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Comparing the Vitreous Floaters Functional Questionnaire to the VFQ-25 in Vision Degrading Myodesopsia from Vitreous Floaters

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Comparing the Vitreous Floaters Functional Questionnaire to the VFQ-25 in Vision Degrading Myodesopsia from Vitreous Floaters
HIGHLIGHTS • The Vitreous Floaters Functional Questionnaire (VFFQ) is a validated PRO that quantifies the impact of vision degrading myodesopsia from vitreous floaters on visual quality-of-life. • The VFFQ correlates…
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Defocus Incorporated Multiple Segments (DIMS) Spectacle Lenses Versus Single-Vision Lenses for Pediatric Myopia: A Systematic Review and Meta-Analysis

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Defocus Incorporated Multiple Segments (DIMS) Spectacle Lenses Versus Single-Vision Lenses for Pediatric Myopia: A Systematic Review and Meta-Analysis
TOPIC This systematic review and meta-analysis aimed to evaluate the 12-month effectiveness of defocus incorporated multiple segments (DIMS) spectacle lenses compared with single-vision (SV) lenses in slowing myopia progression in…
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Outer Retinal Erosion and Outer Retinal Pinching at the Origin of Subretinal Fluid in Central Serous Chorioretinopathy

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Outer Retinal Erosion and Outer Retinal Pinching at the Origin of Subretinal Fluid in Central Serous Chorioretinopathy
Highlights • Focal erosion and pinching of outer retina are early changes occurring at the origin of fluid in central serous chorioretinopathy. • Subretinal fibrin is a distinctive feature of…
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Mismatch Repair Deficiency in Benign and Atypical Ocular Sebaceous Neoplasms: Implications for Muir-Torre Screening and Classification

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Mismatch Repair Deficiency in Benign and Atypical Ocular Sebaceous Neoplasms: Implications for Muir-Torre Screening and Classification
Highlights • Ocular sebaceous adenomas and atypical sebaceous neoplasms are frequently MMR-deficient. • Atypical sebaceous neoplasms share similar clinicopathologic features with sebaceous adenomas. • Atypical sebaceous neoplasms are intermediate-grade, MMR-deficient,…
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