Ocular Hypotensive Safety and Systemic Absorption of AR-13324 Ophthalmic Solution in Normal Volunteers
Purpose To evaluate the ocular and systemic safety and systemic absorption of AR-13324 in normotensive, healthy volunteers. Design Open-label, noncomparative, single-arm phase 1 clinical trial. Methods setting : Phase 1…
Choroidal Thickness in Nonarteritic Anterior İschemic Optic Neuropathy
We read with interest the article entitled “Choroidal Thickness in Nonarteritic Anterior Ischemic Optic Neuropathy,” by Schuster and associates. The authors have investigated the choroidal thicknesses (CT) in patients who…
High Myopia–Excavated Optic Disc Anomaly Associated With a Frameshift Mutation in the MYC-Binding Protein 2 Gene ( MYCBP2)
Purpose To investigate the ocular and neurologic manifestations, and to identify the causative mutation in a family with an excavated optic disc anomaly, high myopia, enlarged axial lengths, and abnormal…
Color Fundus Photography Versus Fluorescein Angiography in Identification of the Macular Center and Zone in Retinopathy of Prematurity
Purpose To examine the usefulness of fluorescein angiography (FA) in identifying the macular center and diagnosis of zone in patients with retinopathy of prematurity (ROP). Design Validity and reliability analysis…
Highly Reflective Line in Optical Coherence Tomography Images of Eyes With Macular Edema Associated With Branch Retinal Vein Occlusion
Purpose To determine whether the highly reflective vertical lines seen in spectral-domain optical coherence tomographic (SD OCT) images, which we have termed track lines , after resolution of macular edema…
The Effect of Light Deprivation in Patients With Stargardt Disease
Purpose To investigate whether long-term protection from light exposure affects the rate of disease progression in patients with autosomal recessive Stargardt disease (STGD1), measured using fundus autofluorescence imaging. Design Longitudinal,…
Relationship Between Aqueous Flare and Visual Function in Retinitis Pigmentosa
Purpose To investigate the correlation between aqueous flare values and central visual function in patients with retinitis pigmentosa (RP). Design Retrospective, observational case series. Methods We retrospectively studied 160 patients…
Risk Factors for Progressive Myopia in the Atropine Therapy for Myopia Study
Purpose To investigate variables associated with myopic progression despite treatment in the Atropine in the Treatment of Myopia Study. Design Retrospective cohort study. Methods Two hundred of 400 children were…
International Photographic Classification and Grading System for Myopic Maculopathy
Purpose To develop a classification and grading system for myopic maculopathy. Design Development and evaluation of a classification system for myopic maculopathy based on observational case series. Methods A comprehensive…
