A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

Purpose To identify reliable criteria based on spectral-domain optical coherence tomography (SD OCT) to monitor disease progression in geographic atrophy attributable to age-related macular degeneration (AMD) compared with lesion size…

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Photoreceptor Perturbation Around Subretinal Drusenoid Deposits as Revealed by Adaptive Optics Scanning Laser Ophthalmoscopy

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Photoreceptor Perturbation Around Subretinal Drusenoid Deposits as Revealed by Adaptive Optics Scanning Laser Ophthalmoscopy

Purpose To describe the microscopic structure of photoreceptors impacted by subretinal drusenoid deposits, also called pseudodrusen, an extracellular lesion associated with age-related macular degeneration (AMD), using adaptive optics scanning laser…

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Anti-VEGF Treatment Patterns for Neovascular Age-Related Macular Degeneration Among Medicare Beneficiaries

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Anti-VEGF Treatment Patterns for Neovascular Age-Related Macular Degeneration Among Medicare Beneficiaries

Purpose To examine the use of anti–vascular endothelial growth factor (VEGF) therapy in clinical practice among patients with neovascular age-related macular degeneration (AMD). Design Retrospective cohort study. Methods Among 459…

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Ultrastructural Changes of the Vitreoretinal Interface During Long-Term Follow-up After Removal of the Internal Limiting Membrane

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Ultrastructural Changes of the Vitreoretinal Interface During Long-Term Follow-up After Removal of the Internal Limiting Membrane

Purpose To investigate long-term ultrastructural changes in the retina after internal limiting membrane (ILM) peeling through the examination of morphologic changes 3 years after vitrectomy in cynomolgus monkeys. Design Laboratory…

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Suppression of Intraocular Vascular Endothelial Growth Factor During Aflibercept Treatment of Age-Related Macular Degeneration

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Suppression of Intraocular Vascular Endothelial Growth Factor During Aflibercept Treatment of Age-Related Macular Degeneration

Purpose To determine the duration of suppression of aqueous humor concentrations of vascular endothelial growth factor (VEGF) in eyes with neovascular age-related macular degeneration (AMD) treated with aflibercept. Design Nonrandomized…

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Lipids, Lipid Genes, and Incident Age-Related Macular Degeneration: The Three Continent Age-Related Macular Degeneration Consortium

Jan 8, 2017 by in OPHTHALMOLOGY Comments Off on Lipids, Lipid Genes, and Incident Age-Related Macular Degeneration: The Three Continent Age-Related Macular Degeneration Consortium

Purpose To describe associations of serum lipid levels and lipid pathway genes to the incidence of age-related macular degeneration (AMD). Design Meta-analysis. Methods setting : Three population-based cohorts. population :…

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