Purpose To determine the clinical and ultrasound biomicroscopy (UBM) features associated with growth in iris melanocytic lesions. Study Design Retrospective case series analysis. Methods We included all iris melanocytic lesions…
Purpose To investigate the clinical and genetic features of late-onset Fuchs corneal dystrophy (FCD) on Tangier, an island in the Chesapeake Bay with an isolated population of approximately 500 individuals….
Purpose To investigate the efficacy and safety of an investigational integrin antagonist (SAR 1118) ophthalmic solution compared to placebo (vehicle) in subjects with dry eye disease. Design Multicenter, prospective, double-masked,…
Carl Koller (1837-1944) became known in Vienna at the age of 26 when he first appreciated the usefulness of cocaine as a local anesthetic in ophthalmology. He nonetheless decided that…
Purpose To evaluate the safety and possible efficacy of subconjunctival sirolimus for the treatment of chronic active anterior uveitis. Design Prospective, nonrandomized, open-label clinical trial. Methods This single-center pilot trial…
Purpose To evaluate the efficacy of quantitative real-time polymerase chain reaction (qPCR) in the diagnosis of postoperative bacterial endophthalmitis among patients who underwent cataract surgery at a tertiary care center….
Purpose To determine the prevalence of inflammatory back pain in an anterior uveitis cohort. Design Retrospective cohort study. Methods Patients with anterior uveitis were recruited from the clinic of an…
Purpose To estimate the incidence of cytomegalovirus (CMV) retinitis in the era of highly active antiretroviral therapy (HAART) and to characterize the factors associated with increased risk of CMV retinitis….
Three very different methods are currently used to repair acute retinal detachments. Elsewhere in this issue of the Journal , Hwang reviews data obtained from Medicare part B summaries, finding…
