of Ocular Angiogenesis Shozo Sonoda • Parameswaran G. Sreekumar • Ram Kannan • David R. Hinton Introduction Physiologic angiogenesis is carefully regulated by a critical balance between endogenous stimulators and…
and Complications Elias Reichel INTRODUCTION Intravitreal injections are becoming an increasingly common part of clinical practice. In the past, indications for injection of substances into the vitreous cavity were relatively…
FIGURE 6.1. The cyclooxygenase cascade. COX-1 and COX-2 catalyze the biosynthesis of prostanoids (prostaglandins and thromboxane) from membrane-derived arachidonic acid. The prostanoids then bind to their cognate GPCRs (G-protein coupled…
However, when new blood vessels grew into the small tumors from the adjacent vascularized tissues of the eye, for example, retina or iris, the tumors grew quickly and overtook the…
