Ophthalmic Assessment in Patients With Darier Disease
Purpose To assess the prevalence of ophthalmic findings in patients with Darier disease, an autosomal dominant genetic skin disorder, in an effort to evaluate the need for eye examinations in…
Peripheral Monocyte Count and Age-Related Macular Degeneration. The Tongren Health Care Study
Purpose To assess potential associations between the prevalence of age-related macular degeneration (AMD) and systemic parameters in a Chinese population. Design Cross-sectional study. Methods The Tongren Health Care Study included…
Impact of Baseline Characteristics on Geographic Atrophy Progression in the FILLY Trial Evaluating the Complement C3 Inhibitor Pegcetacoplan
Purpose To evaluate the effect of select baseline characteristics on geographic atrophy (GA) progression in eyes receiving intravitreal pegcetacoplan or sham. Design Phase 2 multicenter, randomized, single-masked, sham-controlled trial. Methods…
Predictive Analytics for Glaucoma Using Data From the All of Us Research Program
Purpose To (1) use All of Us ( AoU ) data to validate a previously published single-center model predicting the need for surgery among individuals with glaucoma, (2) train new…
Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend for Macular Edema in Central Retinal Vein Occlusion: the CENTERA Study
Highlights • From baseline to week 76, 65.6% of patients gained ≥15 letters. • In the treat-and-extend phase, 45.0% of patients achieved a mean treatment interval of ≥8 weeks. •…
Randomized, Double-Masked, Pilot Study of Netarsudil 0.02% Ophthalmic Solution for Treatment of Corneal Edema in Fuchs Dystrophy
Purpose To evaluate off-label use of netarsudil 0.02% for treatment of corneal edema associated with Fuchs dystrophy. Design Prospective, randomized clinical trial. Methods Twenty-nine subjects with symptomatic Fuchs dystrophy were…
Ocular Injury Associated With Prone Positioning in Adult Critical Care: A Systematic Review and Meta-Analysis
Purpose Prone positioning during the COVID-19 pandemic has become increasingly used as an adjunct to increase oxygenation in critical care patients. It is associated with an adverse event profile. This…
Tube Versus Trabeculectomy IRIS Ⓡ Registry 1-Year Composite Outcome Analysis with Comparisons to the Randomized Controlled Trial
Highlights • TVT IRIS Registry 1-year composite outcome results differ from those of the TVT RCT. • TVT IRIS Registry tube and trabeculectomy failure rates are not significantly different. •…
The Impact of COVID-19 on Individuals Across the Spectrum of Visual Impairment
Purpose TO assess perceptions and implications of COVID-19 infection across the spectrum of individuals with visually impairment (VI) and those with normal sight. Design Prospective cross-sectional comparative study. Methods Setting:…
A Biomechanical Study of Flanged Intrascleral Haptic Fixation of Three-Piece Intraocular Lenses
Purpose Flanged intrascleral haptic fixation (FISHF) is a useful method for securing intraocular lenses (IOLs) in eyes without capsular support. Biomechanical studies were conducted to support the use of this…
