Surgical Innovations
This article reviews the evidence behind surgical innovations and effect on treatment-related morbidity to examine how they may be integrated into modern management strategies for oral cavity and oropharyngeal squamous…
Advances in Radiation Oncology for the Management of Oropharyngeal Tumors
The major benefits of modern radiation therapy (eg, intensity-modulated [x-ray] radiation therapy [IMRT]) for oropharyngeal cancer are reduced xerostomia and better quality of life. Intensity-modulated proton therapy may provide additional…
Oral Premalignancy
Premalignancy and chemoprevention studies in head and neck cancer typically focus on the oral cavity. Avoiding or cessation of alcohol and smoking, early detection of potentially malignant disorders or cancer,…
Why Otolaryngologists Need to be Aware of Fanconi Anemia
Fanconi anemia (FA) is a rare disorder inherited in an autosomal recessive fashion, with an estimated incidence of 1:360,000 births. Although hematologic complications are the most common manifestation of this…
Oral Cavity and Oropharyngeal Squamous Cell Carcinoma Genomics
Recent technological advances now permit the study of the entire cancer genome, which can elucidate complex pathway interactions that are not apparent at the level of single genes. In this…
Impact of Human Papillomavirus on Oropharyngeal Cancer Biology and Response to Therapy
Oropharyngeal squamous cell carcinoma (OPSCC) originating from human papillomavirus infection has emerged as a new entity in head and neck cancer, defining a subset of patients with distinct carcinogenesis, risk…
Epidemiology of Oral-Cavity and Oropharyngeal Carcinomas
Although tobacco prevalence is declining in most developed countries, less developed countries are still experiencing an increase in tobacco use. Thus the future burden of oral-cavity and oropharyngeal cancers in…
A Tale of Two Cancers: Carcinomas of the Oral Cavity and Oropharynx
Jeffrey N. Myers, MD, PhD, Editor Erich M. Sturgis, MD, MPH, Editor Key points • Oral cavity cancer and oropharyngeal cancer are now considered 2 distinct diseases with differences in…
Application of Autologous Free Tissue Transfer in the Management of Massive Traumatic Tissue Loss
This review describes a general approach and philosophy in the management of massive facial trauma with extensive tissue loss, with particular highlight on the role of free tissue transfer. Key…
Improving Posttraumatic Facial Scars
Posttraumatic soft-tissue injuries of the face are often the most lasting sequelae of facial trauma. The disfigurement of posttraumatic scarring lies in both their physical deformity and psychosocial ramifications. This…
