A Phase 2 Randomized, Double-Masked, Placebo-Controlled Study of a Novel Integrin Antagonist (SAR 1118) for the Treatment of Dry Eye

Jan 12, 2017 by in OPHTHALMOLOGY Comments Off on A Phase 2 Randomized, Double-Masked, Placebo-Controlled Study of a Novel Integrin Antagonist (SAR 1118) for the Treatment of Dry Eye

Purpose To investigate the efficacy and safety of an investigational integrin antagonist (SAR 1118) ophthalmic solution compared to placebo (vehicle) in subjects with dry eye disease. Design Multicenter, prospective, double-masked,…

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AJO History of Ophthalmology Series

Jan 12, 2017 by in OPHTHALMOLOGY Comments Off on AJO History of Ophthalmology Series

Carl Koller (1837-1944) became known in Vienna at the age of 26 when he first appreciated the usefulness of cocaine as a local anesthetic in ophthalmology. He nonetheless decided that…

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Subconjunctival Sirolimus for the Treatment of Chronic Active Anterior Uveitis: Results of a Pilot Trial

Jan 12, 2017 by in OPHTHALMOLOGY Comments Off on Subconjunctival Sirolimus for the Treatment of Chronic Active Anterior Uveitis: Results of a Pilot Trial

Purpose To evaluate the safety and possible efficacy of subconjunctival sirolimus for the treatment of chronic active anterior uveitis. Design Prospective, nonrandomized, open-label clinical trial. Methods This single-center pilot trial…

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