Outcomes of Glaucoma Drainage Device Implantation and Trabeculectomy With Mitomycin C in Glaucoma Secondary to Aniridia

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Outcomes of Glaucoma Drainage Device Implantation and Trabeculectomy With Mitomycin C in Glaucoma Secondary to Aniridia

Purpose To compare the outcomes of Aurolab aqueous drainage implant (AADI; Aurolab) placement and trabeculectomy with mitomycin C (MMC) in patients with glaucoma secondary to aniridia. Design Retrospective comparative interventional…

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Endophthalmitis Prophylaxis Failures in Patients Injected With Intracameral Antibiotic During Cataract Surgery

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Endophthalmitis Prophylaxis Failures in Patients Injected With Intracameral Antibiotic During Cataract Surgery

Highlights • No statistical difference exists in endophthalmitis rate between moxifloxacin and cefuroxime. • Successful endophthalmitis prophylaxis depends on intracameral moxifloxacin dose. • Intracameral cefuroxime does not cover Enterococcus and…

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Pentosan Polysulfate Maculopathy: Prevalence, Spectrum of Disease, and Choroidal Imaging Analysis Based on Prospective Screening

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Pentosan Polysulfate Maculopathy: Prevalence, Spectrum of Disease, and Choroidal Imaging Analysis Based on Prospective Screening

Abstract Purpose: To describe the prevalence and spectrum of disease of pentosan polysulfate (PPS) maculopathy in a large multimodal retinal imaging study and to report the results of choroidal vascularity index…

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Impact of Baseline Characteristics on Geographic Atrophy Progression in the FILLY Trial Evaluating the Complement C3 Inhibitor Pegcetacoplan

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Impact of Baseline Characteristics on Geographic Atrophy Progression in the FILLY Trial Evaluating the Complement C3 Inhibitor Pegcetacoplan

Purpose To evaluate the effect of select baseline characteristics on geographic atrophy (GA) progression in eyes receiving intravitreal pegcetacoplan or sham. Design Phase 2 multicenter, randomized, single-masked, sham-controlled trial. Methods…

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Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend for Macular Edema in Central Retinal Vein Occlusion: the CENTERA Study

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Efficacy and Safety of Intravitreal Aflibercept Treat-and-Extend for Macular Edema in Central Retinal Vein Occlusion: the CENTERA Study

Highlights • From baseline to week 76, 65.6% of patients gained ≥15 letters. • In the treat-and-extend phase, 45.0% of patients achieved a mean treatment interval of ≥8 weeks. •…

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Randomized, Double-Masked, Pilot Study of Netarsudil 0.02% Ophthalmic Solution for Treatment of Corneal Edema in Fuchs Dystrophy

Jul 10, 2021 by in OPHTHALMOLOGY Comments Off on Randomized, Double-Masked, Pilot Study of Netarsudil 0.02% Ophthalmic Solution for Treatment of Corneal Edema in Fuchs Dystrophy

Purpose To evaluate off-label use of netarsudil 0.02% for treatment of corneal edema associated with Fuchs dystrophy. Design Prospective, randomized clinical trial. Methods Twenty-nine subjects with symptomatic Fuchs dystrophy were…

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