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Purpose The ROCC study (randomized study comparing ranibizumab to sham in patients with macular edema secondary to central Retinal vein OCClusion [CRVO]) evaluated the short-term effect of intravitreal ranibizumab injections…

Purpose To identify the inherent complexities in assigning causation in the evolving systems era of pediatric ophthalmology. Design Philosophical analysis of causality as it pertains to understanding the pathogenesis of…