Refractory Chronic Rhinosinusitis
Abtin Tabaee, MD, Editor Edward D. McCoul, MD, MPH, Editor The past decade has witnessed a dramatic increase in the quality and volume of research into the basic science underpinnings…
OTOLARYNGOLOGY
Chronic Rhinosinusitis: A “Simple” Complex Condition
Sujana S. Chandrasekhar, MD, FACS, Consulting Editor Often in medicine, what seems simple is actually very complex. That is the case with chronic rhinosinusitis (CRS). CRS is a common chronic…
Population-Based Results in the Management of Sinonasal and Ventral Skull Base Malignancies
Population-based cancer registries allow for data collection on the scale of large populations, outside the limits of a single institution, and facilitate study of rare entities. The SEER database has…
Survival, Morbidity, and Quality-of-Life Outcomes for Sinonasal and Ventral Skull Base Malignancies
Key points • Sinonasal and ventral skull base malignancies are rare and this has made it difficult to conduct randomized controlled trials. Much knowledge of the clinical outcomes for these…
The Role of Targeted Therapy in the Management of Sinonasal Malignancies
Cancers develop secondary to genetic and epigenetic changes that provide the cell with a survival advantage that promotes cellular immortality. Malignancy arises when tumors use mechanisms to evade detection and…
The Making of a Skull Base Team and the Value of Multidisciplinary Approach in the Management of Sinonasal and Ventral Skull Base Malignancies
Key points • Endoscopic endonasal surgery is true team surgery with concurrent participation of different surgical specialties. • Benefits of a multidisciplinary team include cross-fertilization of ideas, surgical innovation, and…
The Role of Chemotherapy in the Management of Sinonasal and Ventral Skull Base Malignancies
Key points • In most cases of advanced sinonasal and ventral skull base cancer, a multimodal treatment approach provides the best chance for improved outcomes. • Depending on the tumor…
Management of Skull Base Defects After Surgical Resection of Sinonasal and Ventral Skull Base Malignancies
Over the past 2 decades, there has been a significant increase in the resection of larger and more complex ventral skull base malignancies. The resection of these lesions has resulted…
The Role of Radiation Therapy in the Management of Sinonasal and Ventral Skull Base Malignancies
Key points • Sinonasal and ventral skull base cancers encompass a variety of rare “orphan” tumors. Existing evidence is predominantly from retrospective single-institution series. • Multimodality treatment with surgery and…
The Role of Robotic Surgery in Sinonasal and Ventral Skull Base Malignancy
Over the past decade, robotic surgery has gained wide popularity, making a significant impact on multiple surgical specialties. In the head and neck arena, transoral robotic surgery has proven to…
