Pharmacologic Management of Cough
This review is an update of recent advances in our understanding of cough suppressants and impairment of cough. Low-dose oral morphine has recently been shown to significantly suppress chronic cough,…
OTOLARYNGOLOGY
Rhinogenic Laryngitis, Cough, and the Unified Airway
Over the past 10 years, there has been increasing recognition of the interaction between the upper and lower airways in patients with a variety of infectious and inflammatory illnesses, including…
Cough Due to Asthma, Cough-Variant Asthma and Non-Asthmatic Eosinophilic Bronchitis
Among the most common causes of chronic cough are asthma (25%) and nonasthmatic eosinophilic bronchitis (10%). In asthma, cough may present as an isolated symptom, in which case it is…
Reflux and Cough
Reflux is a significant contributor to cough in otolaryngology practice; cough is just one marker of its many negative effects on the upper aerodigestive tract. Reflux causes cough both by…
Occupational, Environmental, and Irritant-Induced Cough
Occupational and environmental irritants play a role in the pathogenesis of chronic cough. An irritant is a non-corrosive chemical, which causes a reversible inflammatory change on living tissue by chemical…
The Role of Voice Therapy in the Management of Paradoxical Vocal Fold Motion, Chronic Cough, and Laryngospasm
This article describes the assessment and behavioral treatment for paradoxical vocal fold motion disorder (PVFM), chronic cough, and laryngospasm. Behavioral treatment for these disorders is coordinated by the speech–language pathologist….
Vocal Cord Dysfunction, Paradoxic Vocal Fold Motion, or Laryngomalacia? Our Understanding Requires an Interdisciplinary Approach
This article presents disorders of periodic occurrence of laryngeal obstruction (POLO) resulting in noisy breathing and dyspnea and a variety of secondary symptoms. Included in this classification are glottic disorders,…
Evidence for Sensory Neuropathy and Pharmacologic Management
Recent literature points to postviral sensory neuropathy as a possible cause for refractory chronic cough. Vagal neuropathy may affect the sensory branches, inducing chronic cough or laryngospasm. Although the clinical…
Cough and Swallowing Dysfunction
The symptom of cough may result from a multitude of etiologies involving different parts of the aerodigestive tract. This article focuses on the association of cough and swallowing dysfunction in…
Afferent Nerves Regulating the Cough Reflex: Mechanisms and Mediators of Cough in Disease
Bronchopulmonary C fibers and acid-sensitive, capsaicin-insensitive mechanoreceptors innervating the larynx, trachea, and large bronchi regulate the cough reflex. These vagal afferent nerves may interact centrally with sensory input arising from…
