OPHTHALMOLOGY
Risk Factors for Glaucoma Drainage Device Revision or Removal Using the IRIS Registry
PURPOSE To elucidate risk factors for revision or removal of glaucoma drainage devices (GDD) in glaucoma patients in the United States. DESIGN Retrospective cohort study. METHODS IRIS Registry (Intelligent Research…
Prevalence of the Infantile Strabismus Complex in Premature Children With and Without Periventricular Leukomalacia
Purpose To determine whether rates of strabismus and associated visuomotor deficits differed among children with different severities of periventricular leukomalacia (PVL). Design Retrospective, case-control study. Methods Brain magnetic resonance images…
Pigmented posterior lenticonus in unilateral development cataract
BRIEF SUMMARY STATEMENT This is a rare case of unilateral developmental cataract characterized by posterior lenticonus with pigment inside the lens capsule. CASE REPORT A ten-year-old boy presented with progressive…
Atypical conjunctival hyaline deposition in a case of granular corneal dystrophy type 2
A 43-year-old woman diagnosed with granular corneal dystrophy (GCD) type 2 on the basis of bilateral granular deposition in the corneal stroma ( Fig. 1 A) and the detection of a…
Personalized Model to Predict Keratoconus Progression From Demographic, Topographic, and Genetic Data
PURPOSE To generate a prognostic model to predict keratoconus progression to corneal crosslinking (CXL). DESIGN Retrospective cohort study. METHODS We recruited 5025 patients (9341 eyes) with early keratoconus between January…
Three‐Year Safety Results of SAR422459 (EIAV‐ABCA4) Gene Therapy in Patients With ABCA4‐Associated Stargardt Disease: An Open‐Label Dose‐Escalation Phase I/IIa Clinical Trial, Cohorts 1‐5
Purpose To report on the safety of the first 5 cohorts of a gene therapy trial using recombinant equine infectious anemia virus expressing ABCA4 (EIAV-ABCA4) in adults with Stargardt dystrophy…
Long-Term Continuous Assessment of Internal Limiting Membrane Filling Induced Super-Large Macular Hole Healing
Purpose To assess the long-term continuous anatomical and functional healing process of a super-large full-thickness macular hole (FTMH) after internal limiting membrane (ILM) filling and air tamponade. Design Prospective, interventional…
Topical Pharmacologic Interventions Versus Active Control, Placebo, or No Treatment for Epidemic Keratoconjunctivitis :Findings From a Cochrane Systematic Review
Purpose To summarize key findings from a Cochrane systematic review of the effectiveness and safety of topical pharmacologic interventions compared with active control or placebo for epidemic keratoconjunctivitis (EKC). Design Systematic…
