Purpose To describe the clinical implications of outer foveolar defects on optical coherence tomography (OCT) in eyes treated surgically for macular hole (MH). Design Retrospective observational case series. Methods Ninety-six…
Purpose To evaluate the effects of multiple intravitreal injections of anti–vascular endothelial growth factor (VEGF) agents on the thickness of the retinal nerve fiber layer (RNFL) in patients with wet…
Purpose To determine whether diabetes mellitus is protective for nuclear sclerotic cataract at baseline and 6 and 12 months after vitrectomy surgery. Design Prospective, interventional cohort study. Methods Phakic diabetic…
Purpose To calculate the incidence rates of ocular complications and vision loss in HLA-B27-associated uveitis and to explore the effect of chronic inflammation on clinical outcomes. Design Retrospective longitudinal cohort…
The use of air to attempt to reattach the retina predates Jules Gonin’s discovery of the underlying etiology of rhegmatogenous retinal detachment. In the 1930’s, Rosengren frequently used air to…
Purpose To evaluate outcome of early surgery in vitreous hemorrhage, presumably associated with retinal tears. Design Retrospective, noncomparative interventional case series. Methods We included 40 consecutive cases in 39 patients…
Purpose To evaluate the effects of topically applied bevacizumab and sunitinib on experimentally induced corneal neovascularization. Design Experimental animal study. Methods Thirty-six New Zealand rabbits were involved. One eye per…
Purpose To describe 3 cases of an acute zonal occult outer retinopathy–like illness responsive to valacyclovir hydrochloride. Design Retrospective, interventional case series. Methods Three patients were treated with valacyclovir and…
The AJO encourages authors to report the visual acuity in the manuscript using the same nomenclature that was used in gathering the data provided they were recorded in one of…
Purpose To evaluate the severity of ocular involvement of patients with Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap, and to investigate the relationship of the SCORTEN (a…
