Leukemia Cutis Key Points Leukemia is a cancer of myelogenous and lymphatic precursor blood-forming cells, and with infiltration of the epidermis, dermis, and subcutis it results in extramedullary lesions such…

Kaposi Sarcoma Key Points Kaposi sarcoma (KS) is a low-grade, multicentric, vascular neoplasm Classic KS occurs in elderly men of southern European ancestry, typically on the lower extremities Endemic KS…

Fibrosarcoma Key Points Fibrosarcoma (FS) is a highly malignant tumor of fibrous tissue These tumors predominantly arise from tendons and fascia of deep soft tissues, most often in the extremities,…

Dermatofibrosarcoma Protuberans Key Points Dermatofibrosarcoma protuberans is a fibroblastic cutaneous sarcoma that represents the most common dermal sarcoma It has a very low metastatic potential but has a tendency for…

Basal Cell Carcinoma Key Points Basal cell carcinoma (BCC) is the most common malignant neoplasm of the skin, and in the eyelids it accounts for about 80% to 85% of…

Cutaneous T-Cell Lymphoma Key Points Primary cutaneous T-cell lymphoma is a heterogeneous group of non-Hodgkin lymphomas that is responsible for two-thirds of all cutaneous lymphomas The most common forms are…

Adenoid Cystic Carcinoma Key Points Adenoid cystic carcinoma (ACC) is an epithelial tumor that occurs primarily in the major salivary and lacrimal glands, and the skin can be involved secondarily…

Angiosarcoma Key Points Angiosarcoma is a rare aggressive malignant tumor of vascular origin About 62% occur in the head and neck region, more common in men in the 6th to…

Xanthogranuloma and Histiocytoses Key Points The pathogenesis of xanthogranulomas is unknown, but it is believed that they arise from a reactive, metabolic, or inflammatory process that results in the proliferation…

Xeroderma Pigmentosum Key Points Xeroderma pigmentosum (XP) is an autosomal recessive hereditary disease It is a congenital sensitization of the skin to ultraviolet radiation, due to a defect in normal…