OPHTHALMOLOGY

Microperimetry as an Outcome Measure Improves Patient Eligibility and Efficacy Detection in RPGR Gene Therapy Trials

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Microperimetry as an Outcome Measure Improves Patient Eligibility and Efficacy Detection in RPGR Gene Therapy Trials
Highlights • Microperimetry increases eligibility in RPGR gene therapy trials. • LLVA underestimates treatment response across disease stages. • Microperimetry detects more responders than LLVA at Month 12. • Central…
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Risk Factors and Predictive Model for Postoperative High Myopia in Children Undergoing Congenital Cataract Surgery With Intraocular Lens Implantation

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Risk Factors and Predictive Model for Postoperative High Myopia in Children Undergoing Congenital Cataract Surgery With Intraocular Lens Implantation
Highlights • The IOL/AL ratio is a novel, independent predictor for high myopia in pediatric eyes. • Time-to-event analysis successfully accounts for varying follow-up and censored data. • The model…
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Clinical Outcomes and Genomic Epidemiology of Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Keratitis

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Clinical Outcomes and Genomic Epidemiology of Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Keratitis
Purpose To characterize the clinical features, management, antimicrobial resistance patterns, and genomic epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) keratitis at two North American centers. Design Retrospective interventional case series combined…
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Noncombustible Nicotine or Tobacco Product Use After Smoking Cessation and Major Vision-Impairing Diseases: A Nationwide Cohort Study

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Noncombustible Nicotine or Tobacco Product Use After Smoking Cessation and Major Vision-Impairing Diseases: A Nationwide Cohort Study
HIGHLIGHTS • The ocular safety of switching to NNTPs after smoking cessation remains uncertain. • NNTP switchers had higher risk of major vision-impairing eye diseases. • Risk elevations were greatest…
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Impact of Contact Lens Use on Clinical Profile and Outcomes of Fungal Keratitis: An 8-Year Retrospective Study

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Impact of Contact Lens Use on Clinical Profile and Outcomes of Fungal Keratitis: An 8-Year Retrospective Study
Purpose To compare clinical characteristics, microbiological profiles, treatment strategies, and outcomes between contact lens–associated (CL) and noncontact lens–associated (non-CL) fungal keratitis. Design Retrospective, comparative clinical cohort study. Methods A review…
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Antiadalimumab Antibodies in Patients With Inflammatory Ocular Diseases: Incidence and Clinical Outcomes

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Antiadalimumab Antibodies in Patients With Inflammatory Ocular Diseases: Incidence and Clinical Outcomes
Highlights • Antiadalimumab antibodies occur frequently, ∼50% by 8 years. • Antibodies are associated with lower adalimumab levels and active disease. • Concomitant immunosuppression may reduce risk of antibody formation….
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Application of a Quantitative Vascular Severity Score in Retinopathy of Prematurity in the United States and India: New Insights Into Disease Epidemiology and Pathophysiology

Sep 19, 2026 by in OPHTHALMOLOGY Comments Off on Application of a Quantitative Vascular Severity Score in Retinopathy of Prematurity in the United States and India: New Insights Into Disease Epidemiology and Pathophysiology
PURPOSE To compare the epidemiology and phenotypic characteristics of 2 populations of patients with retinopathy of prematurity (ROP) using a quantitative artificial intelligence (AI)–derived vascular severity score (VSS). METHODS We…
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