Reply to Comment on: Big Data or Big Bias? Interpreting Large-Scale Ophthalmic Studies

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Reply to Comment on: Big Data or Big Bias? Interpreting Large-Scale Ophthalmic Studies

W e appreciate the insightful comments of Vasu and Dorairaj on our editorial about “big data” in ophthalmology. , Although these databases offer immense research opportunities, it is essential for…

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Comment on: Big Data or Big Bias? Interpreting Large-Scale Ophthalmic Studies

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Comment on: Big Data or Big Bias? Interpreting Large-Scale Ophthalmic Studies

W e read with great interest the article by Swaminathan and Medeiros, which discusses key considerations in interpreting large database studies and their direct clinical implications. The authors eloquently delineate…

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Comment on: Seven-Year Clinical Outcomes and Optical Quality of Implantable Collamer Lens Implantation Versus KLEx for Myopia Correction

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Comment on: Seven-Year Clinical Outcomes and Optical Quality of Implantable Collamer Lens Implantation Versus KLEx for Myopia Correction

W e read with great interest the article titled “Seven-Year Clinical Outcomes and Optical Quality of Implantable Collamer Lens Implantation Versus KLEx for Myopia Correction” by Cheng et al. The…

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Deconstructing White Dot Syndromes–Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Deconstructing White Dot Syndromes–Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11

Purpose The term white dot syndromes (WDS) has historically grouped multiple non-infectious posterior uveitis (NIPU) entities based on a similar funduscopic appearance of “white dots.” Despite decades of use, the…

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Comment on “Interferon Alpha-2a as Treatment for Primary Acquired Melanosis With Atypia and for Primary Acquired Melanosis With Atypia Surrounding Conjunctival Melanoma”

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Comment on “Interferon Alpha-2a as Treatment for Primary Acquired Melanosis With Atypia and for Primary Acquired Melanosis With Atypia Surrounding Conjunctival Melanoma”

V aisman et al reported a 93% complete response rate with topical interferon-alpha2a for primary acquired melanosis with atypia over a follow-up exceeding 10 years. Duration is more important than…

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Risk-Stratified Monitoring of Open Angle Glaucoma Suspects Based on Diagnostic Conversion Risk

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Risk-Stratified Monitoring of Open Angle Glaucoma Suspects Based on Diagnostic Conversion Risk

Highlights • Annual OAGS-to-POAG conversion rate is low after year 1 (around 5% per year). • Older, treated suspects had an 8x greater risk than younger, untreated suspects. • Low-risk…

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Prevalence of Chronic Health Conditions by Vision Difficulty Status Among Middle-Aged and Older Adults, United States, 2020-2024

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Prevalence of Chronic Health Conditions by Vision Difficulty Status Among Middle-Aged and Older Adults, United States, 2020-2024

Highlights • This study provides national estimates on the associations between vision difficulty and several chronic health conditions using nationally representative, population-based survey data. • Prevalence of most chronic health…

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Asymmetric Peripheral Retinal Vascular Extension in Anti-Vascular Endothelial Growth Factor–Treated Type 1 Retinopathy of Prematurity: Disparity Between Nasal and Temporal Hemispheres

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Asymmetric Peripheral Retinal Vascular Extension in Anti-Vascular Endothelial Growth Factor–Treated Type 1 Retinopathy of Prematurity: Disparity Between Nasal and Temporal Hemispheres

Highlights • Anti–vascular endothelial growth factor for type 1 retinopathy of prematurity increased nasal and temporal peripheral vascularization. • Anti-vascular endothelial growth factor–treated eyes had marked nasal-temporal disparity in vascular…

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Vitrectomy Versus Observation for Lamellar Macular Holes With Epiretinal Proliferation: A Systematic Review and Meta-Analysis

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Vitrectomy Versus Observation for Lamellar Macular Holes With Epiretinal Proliferation: A Systematic Review and Meta-Analysis

Topic To compare the visual and anatomical outcomes of vitrectomy with those of observation in eyes with lamellar macular holes associated with epiretinal proliferation (LHEP). Clinical relevance LHEP is increasingly…

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Impact of Viewing Distance on the Occurrence Rate of Intermittent Exotropia Revealed by Ambulatory Eye Tracking

Sep 20, 2026 by drzezo in OPHTHALMOLOGY Comments Off on Impact of Viewing Distance on the Occurrence Rate of Intermittent Exotropia Revealed by Ambulatory Eye Tracking

PURPOSE Eye tracking in ambulatory patients permits measurement of the occurrence rate of intermittent exotropia. This information is useful for deciding which patients need surgery. However, viewing distance can influence…

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